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Found 67 result(s)
Exposome-Explorer is the first database dedicated to biomarkers of exposure to environmental risk factors for diseases. It contains detailed information on the nature of biomarkers, populations and subjects where measured, samples analyzed, methods used for biomarker analyses, concentrations in biospecimens, correlations with external exposure measurements, and biological reproducibility over time.
The HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbols and names to over 35,000 human loci, of which around 19,000 are protein coding. This curated online repository of HGNC-approved gene nomenclature and associated resources includes links to genomic, proteomic and phenotypic information, as well as dedicated gene family pages.
<<<!!!<<< Phasing out support for the Database of Genomic Variants archive (DGVa). The submission, archiving, and presentation of structural variation services offered by the DGVa is transitioning to the European Variation Archive (EVA) https://www.re3data.org/repository/r3d100011553. All of the data shown in the DGVa website is already searchable and browsable from the EVA Study Browser. Submission of structural variation data to EVA is done using the VCF format. The VCF specification allows representing multiple types of structural variants such as insertions, deletions, duplications and copy-number variants. Other features such as symbolic alleles, breakends, confidence intervals etc., support more complex events, such as translocations at an imprecise position. >>>!!!>>>
The Infrared Space Observatory (ISO) is designed to provide detailed infrared properties of selected Galactic and extragalactic sources. The sensitivity of the telescopic system is about one thousand times superior to that of the Infrared Astronomical Satellite (IRAS), since the ISO telescope enables integration of infrared flux from a source for several hours. Density waves in the interstellar medium, its role in star formation, the giant planets, asteroids, and comets of the solar system are among the objects of investigation. ISO was operated as an observatory with the majority of its observing time being distributed to the general astronomical community. One of the consequences of this is that the data set is not homogeneous, as would be expected from a survey. The observational data underwent sophisticated data processing, including validation and accuracy analysis. In total, the ISO Data Archive contains about 30,000 standard observations, 120,000 parallel, serendipity and calibration observations and 17,000 engineering measurements. In addition to the observational data products, the archive also contains satellite data, documentation, data of historic aspects and externally derived products, for a total of more than 400 GBytes stored on magnetic disks. The ISO Data Archive is constantly being improved both in contents and functionality throughout the Active Archive Phase, ending in December 2006.
The Expression Atlas provides information on gene expression patterns under different biological conditions such as a gene knock out, a plant treated with a compound, or in a particular organism part or cell. It includes both microarray and RNA-seq data. The data is re-analysed in-house to detect interesting expression patterns under the conditions of the original experiment. There are two components to the Expression Atlas, the Baseline Atlas and the Differential Atlas. The Baseline Atlas displays information about which gene products are present (and at what abundance) in "normal" conditions (e.g. tissue, cell type). It aims to answer questions such as "which genes are specifically expressed in human kidney?". This component of the Expression Atlas consists of highly-curated and quality-checked RNA-seq experiments from ArrayExpress. It has data for many different animal and plant species. New experiments are added as they become available. The Differential Atlas allows users to identify genes that are up- or down-regulated in a wide variety of different experimental conditions such as yeast mutants, cadmium treated plants, cystic fibrosis or the effect on gene expression of mind-body practice. Both microarray and RNA-seq experiments are included in the Differential Atlas. Experiments are selected from ArrayExpress and groups of samples are manually identified for comparison e.g. those with wild type genotype compared to those with a gene knock out. Each experiment is processed through our in-house differential expression statistical analysis pipeline to identify genes with a high probability of differential expression.
SOHO, the Solar & Heliospheric Observatory, is a project of international collaboration between ESA and NASA to study the Sun from its deep core to the outer corona and the solar wind. SOHO was launched on December 2, 1995. The SOHO spacecraft was built in Europe by an industry team led by prime contractor Matra Marconi Space (now EADS Astrium) under overall management by ESA. The twelve instruments on board SOHO were provided by European and American scientists.
Currently, the IMS repository focuses on resources provided by the Institute for Natural Language Processing in Stuttgart (IMS) and other CLARIN-D related institutions such as the local Collaborative Research Centre 732 (SFB 732) as well as institutions and/or organizations that belong to the CLARIN-D extended scientific community. Comprehensive guidelines and workflows for submission by external contributors are being compiled based on the experiences in archiving such in-house resources.
Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.
CERN, DESY, Fermilab and SLAC have built the next-generation High Energy Physics (HEP) information system, INSPIRE. It combines the successful SPIRES database content, curated at DESY, Fermilab and SLAC, with the Invenio digital library technology developed at CERN. INSPIRE is run by a collaboration of CERN, DESY, Fermilab, IHEP, IN2P3 and SLAC, and interacts closely with HEP publishers, arXiv.org, NASA-ADS, PDG, HEPDATA and other information resources. INSPIRE represents a natural evolution of scholarly communication, built on successful community-based information systems, and provides a vision for information management in other fields of science.
The Database of Protein Disorder (DisProt) is a curated database that provides information about proteins that lack fixed 3D structure in their putatively native states, either in their entirety or in part. DisProt is a community resource annotating protein sequences for intrinsically disorder regions from the literature. It classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partner.
EnsemblPlants is a genome-centric portal for plant species. Ensembl Plants is developed in coordination with other plant genomics and bioinformatics groups via the EBI's role in the transPLANT consortium.
Public Opinion in the European Union. Our surveys address major topics concerning European citizenship. The Standard Eurobarometer was established in 1973. Since 1973, the European Commission has been monitoring the evolution of public opinion in the Member States, thus helping the preparation of texts, decision-making and the evaluation of its work. Our surveys and studies address major topics concerning European citizenship: enlargement, social situation, health, culture, information technology, environment, the Euro, defence, etc. Each survey consists of approximately 1000 face-to-face interviews per country. Reports are published twice yearly. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. Special Eurobarometer reports are based on in-depth thematic studies carried out for various services of the European Commission or other EU Institutions and integrated in the Standard Eurobarometer's polling waves. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. Flash Eurobarometers are ad hoc thematic telephone interviews conducted at the request of any service of the European Commission. Flash surveys enable the Commission to obtain results relatively quickly and to focus on specific target groups, as and when required. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. The qualitative studies investigate in-depth the motivations, feelings and reactions of selected social groups towards a given subject or concept, by listening to and analysing their way of expressing themselves in discussion groups or with non-directive interviews.
ECDC is an EU agency aimed at strengthening Europe's defences against infectious diseases. The core functions cover a wide spectrum of activities: surveillance, epidemic intelligence, response, scientific advice, microbiology, preparedness, public health training, international relations, health communication, and the scientific journal Eurosurveillance. Within the field of its mission, the Centre shall: search for, collect, collate, evaluate and disseminate relevant scientific and technical data; provide scientific opinions and scientific and technical assistance including training; provide timely information to the Commission, the Member States, Community agencies and international organisations active within the field of public health; coordinate the European networking of bodies operating in the fields within the Centre's mission, including networks that emerge from public health activities supported by the Commission and operating the dedicated surveillance networks; exchange information, expertise and best practices, and facilitate the development and implementation of joint actions.
The EPN (or EUREF Permanent Network) is a voluntary organization of several European agencies and universities that pool resources and permanent GNSS station data to generate precise GNSS products. The EPN has been created under the umbrella of the International Association Geodesy and more precisely by its sub-commission EUREF. The European Terrestrial Reference System 89 (ETRS89) is used as the standard precise GPS coordinate system throughout Europe. Supported by EuroGeographics and endorsed by the EU, this reference system forms the backbone for all geographic and geodynamic projects on the European territory both on a national as on an international level.
mentha archives evidence collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. The aggregated data forms an interactome which includes many organisms. mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. mentha offers eight interactomes (Homo sapiens, Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Escherichia coli K12, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae) plus a global network that comprises every organism, including those not mentioned. The website and the graphical application are designed to make the data stored in mentha accessible and analysable to all users. Source databases are: MINT, IntAct, DIP, MatrixDB and BioGRID.
M-CSA is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes. There are two kinds of entries in M-CSA. 'Detailed mechanism' entries are more complete and show the individual chemical steps of the mechanism as schemes with electron flow arrows. 'Catalytic Site' entries annotate the catalytic residues necessary for the reaction, but do not show the mechanism. The M-CSA (Mechanism and Catalytic Site Atlas) represents a unified resource that combines the data in both MACiE and the CSA
The Cellular Phenotype database stores data derived from high-throughput phenotypic studies and it is being developed as part of the Systems Microscopy Network of Excellence project. The aim of the Cellular Phenotype database is to provide easy access to phenotypic data and facilitate the integration of independent phenotypic studies. Through its interface, users can search for a gene of interest, or a collection of genes, and retrieve the loss-of-function phenotypes observed, in human cells, by suppressing the expression of the selected gene(s), through RNA interference (RNAi), across independent phenotypic studies. Similarly, users can search for a phenotype of interest and retrieve the RNAi reagents that have caused such phenotype and the associated target genes. Information about specific RNAi reagents can also be obtained when searching for a reagent ID.
As part of the Copernicus Space Component programme, ESA manages the coordinated access to the data procured from the various Contributing Missions and the Sentinels, in response to the Copernicus users requirements. The Data Access Portfolio documents the data offer and the access rights per user category. The CSCDA portal is the access point to all data, including Sentinel missions, for Copernicus Core Users as defined in the EU Copernicus Programme Regulation (e.g. Copernicus Services).The Copernicus Space Component (CSC) Data Access system is the interface for accessing the Earth Observation products from the Copernicus Space Component. The system overall space capacity relies on several EO missions contributing to Copernicus, and it is continuously evolving, with new missions becoming available along time and others ending and/or being replaced.
This classic collection of test cases for validation of turbulence models started as an EU / ERCOFTAC project led by Pr. W. Rodi in 1995. It is maintained by Dr. T. Craft at Manchester since 1999. Initialy limited to experimental data, computational results, and results and conclusions drawn from the ERCOFTAC Workshops on Refined Turbulence Modelling (SIG15). At the moment, each case should contain at least a brief description, some data to download, and references to published work. Some cases contain significantly more information than this.
<<<!!!<<< This repository is no longer available. >>>!!!>>> BioVeL is a virtual e-laboratory that supports research on biodiversity issues using large amounts of data from cross-disciplinary sources. BioVeL supports the development and use of workflows to process data. It offers the possibility to either use already made workflows or create own. BioVeL workflows are stored in MyExperiment - Biovel Group http://www.myexperiment.org/groups/643/content. They are underpinned by a range of analytical and data processing functions (generally provided as Web Services or R scripts) to support common biodiversity analysis tasks. You can find the Web Services catalogued in the BiodiversityCatalogue.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.