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Found 14 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
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With ARS - Antimicrobial Resistance Surveillance in Germany - the infrastructure for a nationwide surveillance of antimicrobial resistance has been established, which covers both the inpatient medical care and the ambulatory care sector. This is intended to reliable data on the epidemiology of antimicrobial resistance in Germany and differential statements provided by structural features of the health care and by region are possible. ARS is designed as a laboratory-based surveillance system for continuous collection of resistance data from routine for the full range of clinically relevant bacterial pathogens. Project participants and thus data suppliers are laboratories that analyze samples of medical facilities and doctors' offices microbiologically.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
The Tropospheric Ozone Assessment Report (TOAR) database of global surface observations is the world's most extensive collection of surface ozone measurements and includes also data on other air pollutants and on weather for some regions. Measurements from 1970 to 2019 (Version 1) have been collected in a relational database, and are made available via a graphical web interface, a REST service (https://toar-data.fz-juelich.de/api/v1) and as aggregated products on PANGAEA (https://doi.pangaea.de/10.1594/PANGAEA.876108). Measurements from 1970 to present (Version 2) are being collected in a relational database, and are made available via a REST service (https://toar-data.fz-juelich.de/api/v2).
DBpedia is a crowd-sourced community effort to extract structured information from Wikipedia and make this information available on the Web. DBpedia allows you to ask sophisticated queries against Wikipedia, and to link the different data sets on the Web to Wikipedia data. We hope that this work will make it easier for the huge amount of information in Wikipedia to be used in some new interesting ways. Furthermore, it might inspire new mechanisms for navigating, linking, and improving the encyclopedia itself.
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Rodare is the institutional research data repository at HZDR (Helmholtz-Zentrum Dresden-Rossendorf). Rodare allows HZDR researchers to upload their research software and data and enrich those with metadata to make them findable, accessible, interoperable and retrievable (FAIR). By publishing all associated research software and data via Rodare research reproducibility can be improved. Uploads receive a Digital Object Identfier (DOI) and can be harvested via a OAI-PMH interface.
The German Text Archive (Deutsches Textarchiv, DTA) presents online a selection of key German-language works in various disciplines from the 17th to 19th centuries. The electronic full-texts are indexed linguistically and the search facilities tolerate a range of spelling variants. The DTA presents German-language printed works from around 1650 to 1900 as full text and as digital facsimile. The selection of texts was made on the basis of lexicographical criteria and includes scientific or scholarly texts, texts from everyday life, and literary works. The digitalisation was made from the first edition of each work. Using the digital images of these editions, the text was first typed up manually twice (‘double keying’). To represent the structure of the text, the electronic full-text was encoded in conformity with the XML standard TEI P5. The next stages complete the linguistic analysis, i.e. the text is tokenised, lemmatised, and the parts of speech are annotated. The DTA thus presents a linguistically analysed, historical full-text corpus, available for a range of questions in corpus linguistics. Thanks to the interdisciplinary nature of the DTA Corpus, it also offers valuable source-texts for neighbouring disciplines in the humanities, and for scientists, legal scholars and economists.
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GESIS preserves (mainly quantitative) social research data to make it available to the scientific research community. The data is described in a standardized way, secured for the long term, provided with a permanent identifier (DOI), and can be easily found and reused through browser-optimized catalogs (https://search.gesis.org/).
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ConsensusPathDB integrates interaction networks in humans (and in the model organisms - yeast and mouse) including binary and complex protein-protein, genetic, metabolic, signaling, gene regulatory and drug-target interactions, as well as biochemical pathways. Data originate from public resources for interactions and interactions curated from the literature. The interaction data are integrated in a complementary manner to avoid redundancies.
DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.
The World Stress Map (WSM) is a global compilation of information on the crustal present-day stress field maintained since 2009 at the Helmholtz Centre Potsdam GFZ German Research Centre for Geosciences. It is a collaborative project between academia and industry that aims to characterize the crustal stress pattern and to understand the stress sources. All stress information is analysed and compiled in a standardized format and quality-ranked for reliability and comparability on a global scale. The WSM is an open-access public database and is used by various academic and industrial institutions working in a wide range of Earth science disciplines such as geodynamics, hazard assessment, hydrocarbon exploitations and engineering.
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The ZBW Digital Long-Term Archive is a dark archive whose sole purpose is to guarantee the long term availability of the objects stored in it. The storage for the ZBW’s digital objects and their representation platforms is maintained by the ZBW division IT-Infrastructures and is not part of the tasks of the group Digital Preservation. The content that the ZBW provides is accessible via special representation platforms. The special representation platforms are: EconStor: an open access publication server for literature on business and economics. ZBW DIGITAL ARCHIVE: it contains born digital material from the domains of business and economics. The content of this archive is accessible in open access via EconBiz, the subject portal for business and economics of the ZBW. National and Alliance Licenses: the ZBW negotiates and curates licenses for electronic products on a national level. This is processed under the framework of the German Research Foundation as well as the Alliance of Science Associations, partly with third party funding, partly solely funded by the ZBW. A part of these electronic products is already hosted by the ZBW and counts among the items that are preserved in the digital archive. 20th Century Press Archive: a portal with access to archival material consisting of press clippings from newspapers covering the time period from the beginning of the 20th century to the year 1949.