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Cryo electron microscopy enables the determination of 3D structures of macromolecular complexes and cells from 2 to 100 Å resolution. EMDataResource is the unified global portal for one-stop deposition and retrieval of 3DEM density maps, atomic models and associated metadata, and is a joint effort among investigators of the Stanford/SLAC CryoEM Facility and the Research Collaboratory for Structural Bioinformatics (RCSB) at Rutgers, in collaboration with the EMDB team at the European Bioinformatics Institute. EMDataResource also serves as a resource for news, events, software tools, data standards, and validation methods for the 3DEM community. The major goal of the EMDataResource project in the current funding period is to work with the 3DEM community to (1) establish data-validation methods that can be used in the process of structure determination, (2) define the key indicators of a well-determined structure that should accompany every deposition, and (3) implement appropriate validation procedures for maps and map-derived models into a 3DEM validation pipeline.
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The Global Proteome Machine (GPM) is a protein identification database. This data repository allows users to post and compare results. GPM's data is provided by contributors like The Informatics Factory, University of Michigan, and Pacific Northwestern National Laboratories. The GPM searchable databases are: GPMDB, pSYT, SNAP, MRM, PEPTIDE and HOT.
The Protein Data Bank (PDB) is an archive of experimentally determined three-dimensional structures of biological macromolecules that serves a global community of researchers, educators, and students. The data contained in the archive include atomic coordinates, crystallographic structure factors and NMR experimental data. Aside from coordinates, each deposition also includes the names of molecules, primary and secondary structure information, sequence database references, where appropriate, and ligand and biological assembly information, details about data collection and structure solution, and bibliographic citations. The Worldwide Protein Data Bank (wwPDB) consists of organizations that act as deposition, data processing and distribution centers for PDB data. Members are: RCSB PDB (USA), PDBe (Europe) and PDBj (Japan), and BMRB (USA). The wwPDB's mission is to maintain a single PDB archive of macromolecular structural data that is freely and publicly available to the global community.
OceanSITES is a worldwide system of long-term, deepwater reference stations measuring dozens of variables and monitoring the full depth of the ocean from air-sea interactions down to 5,000 meters. Since 1999, the international OceanSITES science team has shared both data and costs in order to capitalize on the enormous potential of these moorings. The growing network now consists of about 30 surface and 30 subsurface arrays. Satellite telemetry enables near real-time access to OceanSITES data by scientists and the public. OceanSITES moorings are an integral part of the Global Ocean Observing System. They complement satellite imagery and ARGO float data by adding the dimensions of time and depth.
WISER is a self-service platform for data of the Global Networks of Isotopes in Precipitation (GNIP) and Rivers (GNIR), hosted within the IAEA's repository for technical resources (NUCLEUS). GNIP in WISER currently contains over 130,000 records, and stable isotopes are current to the end of 2013, and will be updated as verified data comes in. Parts of the GNIR water isotope data is online as well (synoptic/time series), although we are still in process of verifying and completing GNIR data uploads and for other isotopic parameters over the next year. Check back occasionally for GNIR updates. Tritium data after 2009 is in the process of being updated in the next year. When accessing WISER through the URL https://nucleus.iaea.org/wiser, you will be forwarded to the NUCLEUS log-in page. After entering your user credentials and validation, you will be forwarded to the WISER landing page.
The AERONET (AErosol RObotic NETwork) program is a federation of ground-based remote sensing aerosol networks established by NASA and PHOTONS (PHOtométrie pour le Traitement Opérationnel de Normalisation Satellitaire; Univ. of Lille 1, CNES, and CNRS-INSU) and is greatly expanded by networks (e.g., RIMA, AeroSpan, AEROCAN, and CARSNET) and collaborators from national agencies, institutes, universities, individual scientists, and partners. The program provides a long-term, continuous and readily accessible public domain database of aerosol optical, microphysical and radiative properties for aerosol research and characterization, validation of satellite retrievals, and synergism with other databases. The network imposes standardization of instruments, calibration, processing and distribution.
SCISAT, also known as the Atmospheric Chemistry Experiment (ACE), is a Canadian Space Agency small satellite mission for remote sensing of the Earth's atmosphere using solar occultation. The satellite was launched on 12 August 2003 and continues to function perfectly. The primary mission goal is to improve our understanding of the chemical and dynamical processes that control the distribution of ozone in the stratosphere and upper troposphere, particularly in the Arctic. The high precision and accuracy of solar occultation makes SCISAT useful for monitoring changes in atmospheric composition and the validation of other satellite instruments. The satellite carries two instruments. A high resolution (0.02 cm-¹) infrared Fourier transform spectrometer (FTS) operating from 2 to 13 microns (750-4400 cm-¹) is measuring the vertical distribution of trace gases, particles and temperature. This provides vertical profiles of atmospheric constituents including essentially all of the major species associated with ozone chemistry. Aerosols and clouds are monitored using the extinction of solar radiation at 1.02 and 0.525 microns as measured by two filtered imagers. The vertical resolution of the FTS is about 3-4 km from the cloud tops up to about 150 km. Peter Bernath of the University of Waterloo is the principal investigator. A dual optical spectrograph called MAESTRO (Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation) covers the 400-1030 nm spectral region and measures primarily ozone, nitrogen dioxide and aerosol/cloud extinction. It has a vertical resolution of about 1-2 km. Tom McElroy of Environment and Climate Change Canada is the principal investigator. ACE data are freely available from the University of Waterloo website. SCISAT was designated an ESA Third Party Mission in 2005. ACE data are freely available through an ESA portal.
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<<<!!!<<< 2017-06-02: We recently suffered a server failure and are working to bring the full ORegAnno website back online. In the meantime, you may download the complete database here: http://www.oreganno.org/dump/ ; Data are also available through UCSC Genome Browser (e.g., hg38 -> Regulation -> ORegAnno) https://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=686342163_2it3aVMQVoXWn0wuCjkNOVX39wxy&c=chr1&g=oreganno >>>!!!>>> The Open REGulatory ANNOtation database (ORegAnno) is an open database for the curation of known regulatory elements from scientific literature. Annotation is collected from users worldwide for various biological assays and is automatically cross-referenced against PubMED, Entrez Gene, EnsEMBL, dbSNP, the eVOC: Cell type ontology, and the Taxonomy database, where appropriate, with information regarding the original experimentation performed (evidence). ORegAnno further provides an open validation process for all regulatory annotation in the public domain. Assigned validators receive notification of new records in the database and are able to cross-reference the citation to ensure record integrity. Validators have the ability to modify any record (deprecating the old record and creating a new one) if an error is found. Further, any contributor to the database can comment on any annotation by marking errors, or adding special reports into function as they see fit. These features of ORegAnno ensure that the collection is of the highest quality and uniquely provides a dynamic view of our changing understanding of gene regulation in the various genomes.
The Infrared Space Observatory (ISO) is designed to provide detailed infrared properties of selected Galactic and extragalactic sources. The sensitivity of the telescopic system is about one thousand times superior to that of the Infrared Astronomical Satellite (IRAS), since the ISO telescope enables integration of infrared flux from a source for several hours. Density waves in the interstellar medium, its role in star formation, the giant planets, asteroids, and comets of the solar system are among the objects of investigation. ISO was operated as an observatory with the majority of its observing time being distributed to the general astronomical community. One of the consequences of this is that the data set is not homogeneous, as would be expected from a survey. The observational data underwent sophisticated data processing, including validation and accuracy analysis. In total, the ISO Data Archive contains about 30,000 standard observations, 120,000 parallel, serendipity and calibration observations and 17,000 engineering measurements. In addition to the observational data products, the archive also contains satellite data, documentation, data of historic aspects and externally derived products, for a total of more than 400 GBytes stored on magnetic disks. The ISO Data Archive is constantly being improved both in contents and functionality throughout the Active Archive Phase, ending in December 2006.
The National Science Foundation (NSF) Ultraviolet (UV) Monitoring Network provides data on ozone depletion and the associated effects on terrestrial and marine systems. Data are collected from 7 sites in Antarctica, Argentina, United States, and Greenland. The network is providing data to researchers studying the effects of ozone depletion on terrestrial and marine biological systems. Network data is also used for the validation of satellite observations and for the verification of models describing the transfer of radiation through the atmosphere.