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Found 23 result(s)
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Silkworm Pathogen Database (SilkPathDB) is a comprehensive resource for studying on pathogens of silkworm, including microsporidia, fungi, bacteria and virus. SilkPathDB provides access to not only genomic data including functional annotation of genes and gene products, but also extensive biological information for gene expression data and corresponding researches. SilkPathDB will be help with researches on pathogens of silkworm as well as other Lepidoptera insects.
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Standard, reference material is used for measurement process control and reliability evaluation of measurement results, and plays a key role in important fields such as food safety, international and domestic trade, medicine and health, and environmental monitoring. In order to realize the efficient use and sharing of reference material resources in the whole society, the Institute of Chemistry of China Institute of Metrology (formerly the National Reference Material Research Center), with the support of the Ministry of Science and Technology, launched the "National Reference Material Information Service" at the end of 2003.
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Based on the needs of national scientific and technological innovation for laboratory animal resources, we use various methods such as foreign introduction, domestic collection, independent research and development, and protocol conservation to collect, integrate, and optimize laboratory animal resources. The resource library now preserves more than 200 varieties and strains in four categories, including mice, rats, guinea pigs, and rabbits, including routine laboratory animals, genetically modified animal models, and animal models for disease. The predecessor of the resource bank was the National Rodent Laboratory Animal Seed Center (Guoke Cai Zi [1998] No. 010), established in 1998 and based on the Laboratory Animal Resources Research Institute of the Chinese National Academy of Food and Drug Administration.
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The center is a national-level cell bank that is in line with international standards, has complete collections, and is rich in data. The center mainly collects and preserves various types of cells related to medical and biological research and provides technical services. In addition, it also conducts collaborative research and technical training of personnel.
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The National Science and Technology Resource Sharing Service Platform belongs to the national science and technology innovation base of basic support and condition guarantee. Facing the needs of scientific and technological innovation, economic and social development, innovative social governance, and building a safe China, it strengthens the effective integration of high-quality scientific and technological resources and improves the efficiency of scientific and technological resources. Scientific research, technological progress and social development provide networked and socialized scientific and technological resource sharing services.
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The National Center for Forestry and Grassland Genetic Resources (Forestry and Grassland Repository) consists of a series of in situ and ex situ repositories and ex situ repositories, including 15 in situ repositories, 137 ex situ repositories and 3 facility repositories (attached), all of which are recognized by the Seedling Department of the State Forestry and Grassland Administration or the National Forestry Germplasm Resource Platform to collect and preserve forest, grass, flower, bamboo and rattan germplasm resources, and to establish a big data system through standardization, digitization. The purpose of the Forestry and Grassland Resource Bank is to strengthen the germplasm resources of forests, grasses, flowers, bamboos and rattan. The purpose of the Forestry and Grass Resource Bank is to strengthen the collection and preservation of forestry germplasm resources and open sharing, and to promote sustainable use; the objective is to use ultra-low temperature freezing, genomics, artificial intelligence and other high technology to carry out long-term preservation, accurate identification and in-depth exploration of germplasm resources, and to achieve safe preservation and efficient use of germplasm resources. The Forestry and Grassland Resource Bank undertakes the rendezvous of scientific and technological projects in the forestry germplasm resource category. By building an integrated sharing service platform for germplasm resource production, academia and research, it improves the innovation and exploitation capacity of forestry germplasm resources, supports major national needs in scientific research, ecological construction and economic development, promotes the docking of resources and needs, and facilitates the use of resources and the transformation of results. It realizes information and physical sharing, so that forest germplasm resources can be safely preserved and scientifically utilized.
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The center's main task is to introduce, collect and preserve dog laboratory animal varieties, strains, develop and maintain new technologies, cultivate new varieties and strains, and provide standard experimental seeds. In 2019, the Ministry of Science and Technology and the Ministry of Finance, for the purpose of improving the scientific and technological resources sharing service system, promoted the opening and sharing of scientific and technological resources to society, and carried out the optimization and adjustment of the national platform. The National Canine Laboratory Animal Seed Center was successfully approved as the only "National Canine Laboratory Animal Resource Center".
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The National Microbial Resource Center (NMRC) is an important part of the national science and technology resources sharing service platform, responsible for the research, conservation, management and sharing of national microbial strain resources, ensuring the strategic security and sustainable use of microbial strain resources, and providing support for scientific and technological innovation, industrial development and social progress. The main tasks of the NMRC are: to collect, organize and preserve microbial strain resources around national needs and scientific research; to undertake the task of remitting, organizing and preserving strain resources resulting from the implementation of science and technology projects; to be responsible for the development and improvement of microbial strain resource standards, and to standardize and guide the development of microbial strain resources in various fields. The company is responsible for the development and improvement of microbial strain resource standards, standardizing and guiding the protection and utilization of microbial strain resources in various fields; building and maintaining the national strain resource online service system, and carrying out social sharing of physical and information resources of strains; developing key common technologies, creating new resources, and carrying out customized services according to innovative needs; carrying out scientific popularization for the society; carrying out international exchange and cooperation on strain resources, participating in relevant international academic organizations, and safeguarding national interests and Security
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The China National GeneBank database (CNGBdb) is a unified platform for biological big data sharing and application services. CNGBdb has now integrated a large amount of internal and external biological data from resources such as CNGB, NCBI, and the EBI. There are several sub-databases in CNGBdb, including literature, variation, gene, genome, protein, sequence, organism, project, sample, experiment, run, and assembly. Based on underlying big data and cloud computing technologies, it provides various data services, including archive, analysis, knowledge search, and management authorization of biological data. CNGBdb adopts data structures and standards of international omics, health, and medicine, such as The International Nucleotide Sequence Database Collaboration (INSDC), The Global Alliance for Genomics and Health GA4GH (GA4GH), Global Genome Biodiversity Network (GGBN), American College of Medical Genetics and Genomics (ACMG), and constructs standardized data and structures with wide compatibility. All public data and services provided by CNGBdb are freely available to all users worldwide. CNGB Sequence Archive (CNSA) is the bionomics data repository of CNGBdb. CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, and Sequence. Moreover, CNSA has achieved the correlation of sample entities, sample information, and analyzed data on some projects. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in the life science of CNGBdb, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.
WFCC Global Catalogue of Microorganisms (GCM) is expected to be a robust, reliable and user-friendly system to help culture collections to manage, disseminate and share the information related to their holdings. It also provides a uniform interface for the scientific and industrial communities to access the comprehensive microbial resource information.
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The Genome Warehouse (GWH) is a public repository housing genome-scale data for a wide range of species and delivering a series of web services for genome data submission, storage, release and sharing.
WFCC-MIRCEN World Data Centre for Microorganisms (WDCM) provides a comprehensive directory of culture collections, databases on microbes and cell lines, and the gateway to biodiversity, molecular biology and genome projects.The WFCC is a Multidisciplinary Commission of the International Union of Biological Sciences (IUBS) and a Federation within the International Union of Microbiological Societies (IUMS). The WFCC is concerned with the collection, authentication, maintenance and distribution of cultures of microorganisms and cultured cells. Its aim is to promote and support the establishment of culture collections and related services, to provide liaison and set up an information network between the collections and their users, to organise workshops and conferences, publications and newsletters and work to ensure the long term perpetuation of important collections.
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The National Stem Cell Translational Resource Bank (NSCTRB) contains various stem cell resources of both clinical and research grade, especially a sub-bank composed with HLA high-frequency iPSC lines in which the HLA types could match more than 60% of the Chinese population. It can not only provide services to stem cell clinical researches and translation applications, but also provide effective resources for scientific research to the Universities, research institutes, companies, etc. The bank has complete standards, specifications and relevant management systems, and has more than 200 perfessonals in the field of stem cells.
GenBase is a genetic sequence database that accepts user submissions (mRNA, genomic DNAs, ncRNA, or small genomes such as organelles, viruses, plasmids, phages from any organism) and integrates data from INSDC.
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The National Human Brain Tissue Bank for Health and Disease (the Brain Bank) was built to meet the needs of scientific research by integrating experts and forces from neuroscience, human anatomy, pathology and other related disciplines. The Brain Bank collects and stores post-mortem brain tissue donated by patients with various neuropsychiatric disorders and normal controls, as well as their life histories, in accordance with international standards, and provides a detailed and accurate neuropathological diagnosis of these brain tissue samples (also known as the "final diagnosis"). The aim is to discover and elucidate the causes of human neuropsychiatric diseases such as Alzheimer's disease, Parkinson's disease, depression, schizophrenia and other human diseases, and to provide scientists with the most direct and effective means of finding the relevant pathogenesis and establishing effective treatments. The National Brain Tissue Resource for Health and Disease The goal of the National Human Brain Tissue Repository for Health and Disease is to integrate collection, diagnosis, storage and utilisation, and to build a first-class human resource preservation infrastructure in China that is in line with international standards and provides support for neuroscience research. In 2020, the National Brain Bank has established three branches of the National Brain Bank in Hefei, Anhui, Nanjing, Jiangsu, and Shanghai. major cities.
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The National Genomics Data Center (NGDC), part of the China National Center for Bioinformation (CNCB), advances life & health sciences by providing open access to a suite of resources, with the aim to translate big data into big discoveries and support worldwide activities in both academia and industry.
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The National Human Disease Animal Model Resource Bank is supported by the Institute of Medical Laboratory Animals, Chinese Academy of Medical Sciences. The institute is a professional institute engaged in the scientific research and teaching of experimental zoology and comparative medicine. The research unit is the undertaking unit of the national-level laboratory animal technology resource bank for infectious diseases and new drug creation research. In 2015, it established the Key Laboratory of Animal Model Research for Infectious Diseases, the Beijing Engineering Technology Research Center for Laboratory Animal Models of Human Diseases, and established the Human Disease Animal Model Resource Center of the Chinese Academy of Medical Sciences in 2015. The institute has passed CNAS measurement certification, national laboratory accreditation and international AAALAC certification.
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The National Stem Cell Resource Bank (formerly Beijing Stem Cell Bank) was established in 2007 and is a service platform approved by the Ministry of Science and Technology and the Ministry of Finance for the exchange of scientific and technological resources at the national level scientific and technological innovation base of basic supply and state guarantee.
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The construction goal of the national marine aquatic germplasm resource bank: by 2025, promote the national marine aquatic germplasm resource bank to become an international marine aquatic germplasm resource collection and preservation center with rich species, wide coverage, and 200,000 preserved copies. The transformation of resources from decentralized management to centralized integration, from focusing on collection and preservation to focusing on both preservation and development, provides a material basis for promoting the sustainable development of the national economy, building a society in which humans and nature coexist in harmony, and promoting my country's transformation from marine aquatic species to species. The transformation from a country with large quality resources to a country with strong resources.
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The National Microbial Data Center (NMDC) is jointly constructed by the Institute of Microbiology of the Chinese Academy of Sciences (IMS), the Institute of Oceanography of the Chinese Academy of Sciences, the Institute of Infectious Diseases of the Chinese Center for Disease Control and Prevention, the Institute of Plant Physiology and Ecology of the Chinese Academy of Sciences, and the Computer Network Information Centre of the Chinese Academy of Sciences. The General Office of the Chinese Academy of Sciences is the parent department. The data resources covering the whole life cycle of microbiological research, including microbiological resources, microbiological and cross-technological methods, research processes and engineering, microbiomics, microbiological technologies, as well as microbiological literature, patents, experts and results. The Centre focuses on promoting the convergence and integration of scientific and technological resources in the field of microbiology to the national platform, strengthening the development, application and analysis of microbiological resources, enhancing the effective use of microbiological resources and the ability to support scientific and technological innovation, and providing high-quality scientific and technological resource sharing services for scientific research, technological progress and social development.
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From 2005 to 2008, with the support of the Ministry of Science and Technology (MOST), the construction of parasite germplasm repositories has spread to 20 conservation institutions in 15 provinces (cities) nationwide, with 3 physical exhibition halls; 3 live parasite conservation centers. A total of 1115 species/117814 pieces of parasitic germplasm resources of 23 orders in 11 phyla have been integrated into the physical library and database, including human parasites and vectors, animal parasites, plant nematodes, medical insects, trematodes, and parasitic snails, and the resources are combined with moderate distribution, medium- and long-term support, and off-site duplicates. The number of resources accounts for 39.27% of the national total. Through 10 years of accumulation, we have built the largest and only parasite species resource database in the field of parasites in China, and created a sharing platform of parasite germplasm resource center.
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The non-human primate laboratory animal resource bank conducts external services and research through professional preservation institutions, mainly including: research, formulation and improvement of genetic material preservation, breeding technical regulations, innovative technology research, etc.; implementation of information sharing, development of Laboratory technical training, sharing information and technology with scientific research institutions, enterprises and other personnel inside and outside the platform, using network retrieval, telephone consultation, on-site guidance and other forms of communication. The service targets are enterprises, public institutions, social groups, and international organizations engaged in non-human primate genetics and breeding, production, scientific research, and teaching.
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National Aquatic Biological Resource Center (NABRC), established in June 2019, is a member of National Science and Technology Resource Platform supported by the Ministry of Science and Technology and the Ministry of Finance. The NABRC consists of 6 sub-platforms. In summary, these six sub-platforms have reached leading levels at home and abroad in terms of the resource richness, the resource digitization, as well as the amount and quality of resource services. Right now, these platforms are in strong support of basic biology, basic medicine, aquatic economics, water environmental protection and other areas in China. It is an essential way to practice the "Great Yangtze River Protection" and promote the construction of ecological civilization in the Yangtze River. In the future, the platforms will further integrate different types of resources, optimize the resource configuration and improve the service systems, so as to build a high standard resource sharing platform on a global scale and promote international communication and cooperation.