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Found 221 result(s)

BindingDB

The Binding Database

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BindingDB is a public, web-accessible knowledgebase of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. BindingDB supports medicinal chemistry and drug discovery via literature awareness and development of structure-activity relations (SAR and QSAR); validation of computational chemistry and molecular modeling approaches such as docking, scoring and free energy methods; chemical biology and chemical genomics; and basic studies of the physical chemistry of molecular recognition. BindingDB also includes a small collection of host-guest binding data of interest to chemists studying supramolecular systems. The data collection derives from a variety of measurement techniques, including enzyme inhibition and kinetics, isothermal titration calorimetry, NMR, and radioligand and competition assays. BindingDB includes data extracted from the literature and from US Patents by the BindingDB project, selected PubChem confirmatory BioAssays, and ChEMBL entries for which a well defined protein target ("TARGET_TYPE='PROTEIN'") is provided.

Comprehensive Antibiotic Resistance Database

CARD

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A bioinformatic database of antimicrobial resistance genes, their products and associated phenotypes.

OrtholugeDB

The Ortholog Database

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OrtholugeDB contains Ortholuge-based orthology predictions for completely sequenced bacterial and archaeal genomes. It is also a resource for reciprocal best BLAST-based ortholog predictions, in-paralog predictions (recently duplicated genes) and ortholog groups in Bacteria and Archaea. The Ortholuge method improves the specificity of high-throughput orthology prediction.

FAIRDOMHub

The SEEK datafiles

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The FAIRDOMHub is built upon the SEEK software suite, which is an open source web platform for sharing scientific research assets, processes and outcomes. FAIRDOM (Web Site) will establish a support and service network for European Systems Biology. It will serve projects in standardizing, managing and disseminating data and models in a FAIR manner: Findable, Accessible, Interoperable and Reusable. FAIRDOM is an initiative to develop a community, and establish an internationally sustained Data and Model Management service to the European Systems Biology community. FAIRDOM is a joint action of ERA-Net EraSysAPP and European Research Infrastructure ISBE.

PPBio Data Repository

Programa de Pesquisa em Biodiversidade Repositorio de Dados

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The Biodiversity Research Program (PPBio) was created in 2004 with the aims of furthering biodiversity studies in Brazil, decentralizing scientific production from already-developed academic centers, integrating research activities and disseminating results across a variety of purposes, including environmental management and education. PPBio contributes its data to the DataONE network as a member node: https://search.dataone.org/#profile/PPBIO

DisGeNET

A knowledge base for disease genomics

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DisGeNET is a discovery platform containing one of the largest publicly available collections of genes and variants associated to human diseases. DisGeNET integrates data from expert curated repositories, GWAS catalogues, animal models and the scientific literature. DisGeNET data are homogeneously annotated with controlled vocabularies and community-driven ontologies. Additionally, several original metrics are provided to assist the prioritization of genotype–phenotype relationships.

Deep Carbon Observatory Data Portal

DCO-VIVO

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<<<!!!<<< This repository is no longer available. >>>!!!>>>The Deep Carbon Observatory (DCO) is a global community of multi-disciplinary scientists unlocking the inner secrets of Earth through investigations into life, energy, and the fundamentally unique chemistry of carbon. Deep Carbon Observatory Digital Object Registry (“DCO-VIVO”) is a centrally-managed digital object identification, object registration and metadata management service for the DCO. Digital object registration includes DCO-ID generation based on the global Handle System infrastructure and metadata collection using VIVO. Users will be able to deposit their data into the DCO Data Repository and have that data discoverable and accessible by others.

BAliBASE

Benchmark Alignment dataBASE

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A collection of high quality multiple sequence alignments for objective, comparative studies of alignment algorithms. The alignments are constructed based on 3D structure superposition and manually refined to ensure alignment of important functional residues. A number of subsets are defined covering many of the most important problems encountered when aligning real sets of proteins. It is specifically designed to serve as an evaluation resource to address all the problems encountered when aligning complete sequences. The first release provided sets of reference alignments dealing with the problems of high variability, unequal repartition and large N/C-terminal extensions and internal insertions. Version 2.0 of the database incorporates three new reference sets of alignments containing structural repeats, trans-membrane sequences and circular permutations to evaluate the accuracy of detection/prediction and alignment of these complex sequences. Within the resource, users can look at a list of all the alignments, download the whole database by ftp, get the "c" program to compare a test alignment with the BAliBASE reference (The source code for the program is freely available), or look at the results of a comparison study of several multiple alignment programs, using BAliBASE reference sets.

Cassavabase

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Breeding, molecular, genetics and genomics data on cassava (Manihot esculenta) and wild relatives

SOL Genomics Network

SGN

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The Sol Genomics Network (SGN) is a clade-oriented database dedicated to the biology of the Solanaceae family which includes a large number of closely related and many agronomically important species such as tomato, potato, tobacco, eggplant, pepper, and the ornamental Petunia hybrida. SGN is part of the International Solanaceae Initiative (SOL), which has the long-term goal of creating a network of resources and information to address key questions in plant adaptation and diversification

Finnish Biodiversity Information Facility

Laji.fi

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FinBIF is an integral part of the global biodiversity informatics framework, dedicated to managing species information. Its mission encompasses a wide array of services, including the generation of digital data through various processes, as well as the sourcing, collation, integration, and distribution of existing digital data. Key initiatives under FinBIF include the digitization of collections, the development of data systems for collections Kotka (https://biss.pensoft.net/article/37179/) and observations (https://biss.pensoft.net/article/39150/), and the establishment of a national DNA barcode reference library. FinBIF manages data types such as verbal species descriptions (which include drawings, pictures, and other media types), biological taxonomy, scientific collection specimens, opportunistic systematic and event-based observations, and DNA barcodes. It employs a unified IT architecture to manage data flows, delivers services through a single online portal, fosters collaboration under a cohesive umbrella concept, and articulates development visions under a unified brand. The portal Laji.fi serves as the entry point to this harmonized open data ecosystem. FinBIF's portal is accessible in Finnish, Swedish, and English. Data intended for restricted use are made available to authorities through a separate portal, while open data are also shared with international systems, such as GBIF.

VirHostNet

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VirHostNet is a bioinformatic information system dedidacted to the biocuration, data integration, reproducible systems-level analysis and visualisation of Virus / Host protein-protein interactions Network based on graph theory. VirHostNet is an open and gold standard knowledgebase shared in PSI MITAB 2.5 format using the PSICQUIC webservice and distributed through the NDEx platform. VirHostNet is FAIR and is recognized as a COVID-19 ressource by Elixir bio.tools, the European Virus Bioinformatics Center and FAIRsharing.org.

doRiNA

database of RNA interactions in post-transcriptional regulation

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doRiNA is a database of transcriptome-wide binding site data for RNA binding proteins and microRNAs

bii

BioInvestigationIndex

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BioInvestigation Index database enables storing and querying functionalities of experimental biological and biomedical metadata of Leibniz Institute of Plant Biochemistry

MassBank Europe

MassBank

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Database of mass spectra of known, unknown and provisionally identified substances. MassBank is the first public repository of mass spectral data for sharing them among scientific research community. MassBank data are useful for the chemical identification and structure elucidation of chemical compounds detected by mass spectrometry.

BioSimulations

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BioSimulations is a web application for sharing and re-using biomodels, simulations, and visualizations of simulations results. BioSimulations supports a wide range of modeling frameworks (e.g., kinetic, constraint-based, and logical modeling), model formats (e.g., BNGL, CellML, SBML), and simulation tools (e.g., COPASI, libRoadRunner/tellurium, NFSim, VCell). BioSimulations aims to help researchers discover published models that might be useful for their research and quickly try them via a simple web-based interface.

WikiPathways

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WikiPathways was established to facilitate the contribution and maintenance of pathway information by the biology community. WikiPathways is an open, collaborative platform dedicated to the curation of biological pathways. WikiPathways thus presents a new model for pathway databases that enhances and complements ongoing efforts, such as KEGG, Reactome and Pathway Commons. Building on the same MediaWiki software that powers Wikipedia, we added a custom graphical pathway editing tool and integrated databases covering major gene, protein, and small-molecule systems. The familiar web-based format of WikiPathways greatly reduces the barrier to participate in pathway curation. More importantly, the open, public approach of WikiPathways allows for broader participation by the entire community, ranging from students to senior experts in each field. This approach also shifts the bulk of peer review, editorial curation, and maintenance to the community.

DataHub Figshare

University of Hong Kong Data Repository

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Provided by the University Libraries, DataHub is the comprehensive institutional repository for research data and scholarly outputs produced by the researchers and students in the University of Hong Kong and their collaborators.

plankton*net

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The PLANKTON*NET data provider at the Alfred Wegener Institute for Polar and Marine Research is an open access repository for plankton-related information. It covers all types of phytoplankton and zooplankton from marine and freshwater areas. PLANKTON*NET's greatest strength is its comprehensiveness as for the different taxa image information as well as taxonomic descriptions can be archived. PLANKTON*NET also contains a glossary with accompanying images to illustrate the term definitions. PLANKTON*NET therefore presents a vital tool for the preservation of historic data sets as well as the archival of current research results. Because interoperability with international biodiversity data providers (e.g. GBIF) is one of our aims, the architecture behind the new planktonnet@awi repository is observation centric and allows for mulitple assignment of assets (images, references, animations, etc) to any given observation. In addition, images can be grouped in sets and/or assigned tags to satisfy user-specific needs . Sets (and respective images) of relevance to the scientific community and/or general public have been assigned a persistant digital object identifier (DOI) for the purpose of long-term preservation (e.g. set ""Plankton*Net celebrates 50 years of Roman Treaties"", handle: 10013/de.awi.planktonnet.set.495)"

Hustedt Diatom Collection Database

Friedrich Hustedt Diatom Study Centre Database

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<<<!!!<<< This repository is no longer available. PLEASE NOTE: Unfortunately, the Hustedt collection cannot be used at the moment. Since the collection was previously located in our section, this page can still be found here. We hope to be able to provide information on the further use of the collection shortly. https://www.awi.de/en/science/biosciences/polar-biological-oceanography/main-research-focus/hustedt-diatom-study-centre.html >>>!!!>>>

GIS Maps Portal at AWI

maps@awi

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This portal provides an overview of GIS-products at AWI. maps@awi stores and shares public access GIS data created by AWI projects.

iNaturalist.org

iNat

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iNaturalist is a citizen science project and online social network of naturalists, citizen scientists, and biologists built on the concept of mapping and sharing observations of biodiversity across the globe. iNat is a platform for biodiversity research, where anyone can start up their own science project with a specific purpose and collaborate with other observers.

KNB Data Repository

Knowledge Network for Biocomplexity

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The KNB Data Repository is an international repository intended to facilitate ecological, environmental and earth science research in the broadest senses. For scientists, the KNB Data Repository is an efficient way to share, discover, access and interpret complex ecological, environmental, earth science, and sociological data and the software used to create and manage those data. Due to rich contextual information provided with data in the KNB, scientists are able to integrate and analyze data with less effort. The data originate from a highly-distributed set of field stations, laboratories, research sites, and individual researchers. The KNB supports rich, detailed metadata to promote data discovery as well as automated and manual integration of data into new projects. The KNB supports a rich set of modern repository services, including the ability to assign Digital Object Identifiers (DOIs) so data sets can be confidently referenced in any publication, the ability to track the versions of datasets as they evolve through time, and metadata to establish the provenance relationships between source and derived data.

BBMRI-ERIC Directory

Directory of Biobanks

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BBMRI-ERIC is a European research infrastructure for biobanking. We bring together all the main players from the biobanking field – researchers, biobankers, industry, and patients – to boost biomedical research. To that end, we offer quality management services, support with ethical, legal and societal issues, and a number of online tools and software solutions. Ultimately, our goal is to make new treatments possible. The Directory is a tool to share aggregate information about the biobanks that are willing external collaboration. It is based on the MIABIS 2.0 standard, which describes the samples and data in the biobanks at an aggregated level.

Coronavirus Antiviral Research Database

COVDB

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The Coronavirus Antiviral Research Database is designed to expedite the development of SARS-CoV-2 antiviral therapy. It will benefit global coronavirus drug development efforts by (1) promoting uniform reporting of experimental results to facilitate comparisons between different candidate antiviral compounds; (2) identifying gaps in coronavirus antiviral drug development research; (3) helping scientists, clinical investigators, public health officials, and funding agencies prioritize the most promising compounds and repurposed drugs for further development; (4) providing an objective, evidenced-based, source of information for the public; and (5) creating a hub for the exchange of ideas among coronavirus researchers whose feedback is sought and welcomed. By comprehensively reviewing all published laboratory, animal model, and clinical data on potential coronavirus therapies, the Database makes it unlikely that promising treatment approaches will be overlooked. In addition, by making it possible to compare the underlying data associated with competing treatment strategies, stakeholders will be better positioned to prioritize the most promising anti-coronavirus compounds for further development.