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Found 819 result(s)
BindingDB is a public, web-accessible knowledgebase of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. BindingDB supports medicinal chemistry and drug discovery via literature awareness and development of structure-activity relations (SAR and QSAR); validation of computational chemistry and molecular modeling approaches such as docking, scoring and free energy methods; chemical biology and chemical genomics; and basic studies of the physical chemistry of molecular recognition. BindingDB also includes a small collection of host-guest binding data of interest to chemists studying supramolecular systems. The data collection derives from a variety of measurement techniques, including enzyme inhibition and kinetics, isothermal titration calorimetry, NMR, and radioligand and competition assays. BindingDB includes data extracted from the literature and from US Patents by the BindingDB project, selected PubChem confirmatory BioAssays, and ChEMBL entries for which a well defined protein target ("TARGET_TYPE='PROTEIN'") is provided.
WFCC Global Catalogue of Microorganisms (GCM) is expected to be a robust, reliable and user-friendly system to help culture collections to manage, disseminate and share the information related to their holdings. It also provides a uniform interface for the scientific and industrial communities to access the comprehensive microbial resource information.
The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms, entered into the IntAct molecular interaction database (https://www.ebi.ac.uk/intact/). Data includes protein-only complexes as well as protein-small molecule and protein-nucleic acid complexes. All complexes are derived from physical molecular interaction evidences extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background. All complexes are tagged with Evidence and Conclusion Ontology codes to indicate the type of evidence available for each entry.
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Intellectum is the Institutional Repository of the University of La Sabana, has been created to manage, preserve and disseminate the intellectual, scientific, cultural and historical production of the university community.
TiU Dataverse is the central online repository for research data at Tilburg University. The TiU Dataverse is managed by the Research Data Office (RDO) at Library and IT Services (LIS). TiU Dataverse takes part of the DataverseNL network. DataverseNL is a shared data service of several Dutch universities and institutions. The data management is in the hands of the member organizations, while the national organization Data Archiving and Networked Services (DANS) manages the network
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The Yeast Metabolome Database (YMDB) is a manually curated database of small molecule metabolites found in or produced by Saccharomyces cerevisiae (also known as Baker’s yeast and Brewer’s yeast). This database covers metabolites described in textbooks, scientific journals, metabolic reconstructions and other electronic databases.
The EarthEnv project is a collaborative project of biodiversity scientists and remote sensing experts to develop near-global standardized, 1km resolution layers for monitoring and modeling biodiversity, ecosystems, and climate. The work is supported by NCEAS, NASA, NSF, and Yale University.
<<<!!!<<< Pfam data and new releases are available through InterPro https://www.re3data.org/repository/r3d100010798 The Pfam website now serves as a static page with no data updates. All links below redirect to the closest alternative page in the InterPro website. >>>!!!>>>
FactSage is a fully integrated Canadian thermochemical database system which couples proven software with self-consistent critically assessed thermodynamic data. It currently contains data on over 5000 chemical substances as well as solution databases representing over 1000 non-ideal multicomponent solutions (oxides, salts, sulfides, alloys, aqueous, etc.). FactSage is available for use with Windows.
Project Tycho is a repository for global health, particularly disease surveillance data. Project Tycho currently includes data for 92 notifiable disease conditions in the US, and up to three dengue-related conditions for 99 countries. Project Tycho has compiled data from reputable sources such as the US Centers for Disease Control, the World Health Organization, and National health agencies for countries around the world. Project Tycho datasets are highly standardized and have rich metadata to improve access, interoperability, and reuse of global health data for research and innovation.
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The Geodatenkatalog.de is the metadata information system of the Geodateninfrastruktur Deutschland (GDI-DE) and forms the data basis for Geoportal.de. With the help of this central component, metadata for geodata sets, geodata services, and other IT-supported geodata applications are collected and can be researched and retrieved via Geoportal.de.
DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.
The ACTRIS DC is designed to assist scientists with discovering and accessing atmospheric data and contains an up-to-date catalogue of available datasets in a number of databases distributed throughout the world. A site like this can never be complete, but we have aimed at including datasets from the most relevant databases to the ACTRIS project, also building on the work and experiences achieved in the EU FP6 research project Global Earth Observation and Monitoring. The focus of the web portal is validated data, but it is also possible to browse the ACTRIS data server for preliminary data (rapid delivery data) through this site. The web site allows you to search in a local metadata catalogue that contains information on actual datasets that are archived in external archives. It is set up so that you can search for data by selecting the chemical/physical variable, the data location, the database that holds the data, the type of data, the data acquisition platform, and the data matrix
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Stemformatics is a collaboration between the stem cell and bioinformatics community. We were motivated by the plethora of exciting cell models in the public and private domains, and the realisation that for many biologists these were mostly inaccessible. We wanted a fast way to find and visualise interesting genes in these exemplar stem cell datasets. We'd like you to explore. You'll find data from leading stem cell laboratories in a format that is easy to search, easy to visualise and easy to export.
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
UNC Dataverse is an open-source repository software application for archiving, sharing, and accessing research data of all kinds. Each dataverse within the larger repository contains a multitude of datasets, and each dataset contains descriptive metadata and data files. UNC Dataverse is hosted by Odum Institute for Research in Social Science.
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Our system consists of a portal (portal.geomar.de), providing access to several projects with personal password. The portal offers document exchange, common or individual blogs and fora and implementation of external webpages and -services. Moreover, you can access the expedition database, that organizes data description and exchange of cruises and expeditions for each project. Expeditions are linked to KML-files (Google-Earth compatible), allowing a visualization of all stations of a cruise/expedition. We established the linkage to the publications database /repository OceanRep (EPrints), as well as the description of model-output and linkage to paper publications.
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Etsin is a research data finder that contains descriptive information – that is, metadata – on research datasets. In the service you can search and find data from various fields of research. A researcher, research group or organisation can use Etsin to publish information on their datasets and offer them for wider use. The metadata contained in Etsin makes it easy for anyone to discover the datasets. Etsin assigns a permanent URN identifier to datasets, making it possible to link to the dataset and gather merit through its publication and use. The metadata enables users to search for datasets and evaluate the potential for reuse. Etsin includes a description of the dataset, keywords and various dataset identifiers. The dataset information includes, for example, its subject, language, author, owner and how it is licensed for reuse. Good description of data plays an important role in its discoverability and visibility. Etsin encourages comprehensive descriptions by adapting a common set of discipline independent metadata fields and by making it easy to enter metadata. Etsin only collects metadata on datasets, not the data themselves. Anyone may browse and read the metadata. Etsin can be used with a browser or through an open interface (API). The service is discipline independent and free to use. Etsin is a service provided by the Ministry of Education and Culture to actors in the Finnish research system. The service is produced by CSC – IT Center for Science (CSC). Customer service contacts and feedback is available through servicedesk@csc.fi. The service maintenance window is on the fourth Monday of every month between 4 and 6 PM (EET). During that time, the service will be out of use.
ORTOLANG is an EQUIPEX project accepted in February 2012 in the framework of investissements d’avenir. Its aim is to construct a network infrastructure including a repository of language data (corpora, lexicons, dictionaries etc.) and readily available, well-documented tools for its processing. Expected outcomes comprize: promoting research on analysis, modelling and automatic processing of our language to their highest international levels thanks to effective resource pooling; facilitating the use and transfer of resources and tools set up within public laboratories to industrial partners, notably SMEs which often cannot develop such resources and tools for language processing given the cost of investment; promoting French language and the regional languages of France by sharing expertise acquired by public laboratories. ORTOLANG is a service for the language, which is complementary to the service offered by Huma-Num (très grande infrastructure de recherche). Ortolang gives access to SLDR for speech, and CNRTL for text resources.
Institutional repository of the University of Bern. BORIS Portal allows researchers at the University of Bern to archive and manage research data as well as project and funding information, to make it accessible and clearly identifiable.
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DataStream is an open access platform for sharing information on freshwater health. It currently allows users to access, visualize, and download full water quality datasets collected by Indigenous Nations, community groups, researchers and governments throughout five regional hubs: Atlantic Canada, the Great Lakes and Saint Lawrence region, the Lake Winnipeg Basin, the Mackenzie River Basin and the Pacific region. DataStream was developed by The Gordon Foundation and is carried out in collaboration with regional monitoring networks.
BOARD (Bicocca Open Archive Research Data) is the institutional data repository of the University of Milano-Bicocca. BOARD is an open, free-to-use research data repository, which enables members of University of Milano-Bicocca to make their research data publicly available. By depositing their research data in BOARD researchers can: - Make their research data citable - Share their data privately or publicly - Ensure long-term storage for their data - Keep access to all versions - Link their article to their data
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BioSimulators is a registry of containerized biosimulation tools that provide consistent command-line interfaces. The BioSimulations web application helps investigators browse this registry to find simulation tools that have the capabilities (supported modeling frameworks, simulation algorithms, and modeling formats) needed for specific modeling projects.
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FinBIF is an integral part of the global biodiversity informatics framework, dedicated to managing species information. Its mission encompasses a wide array of services, including the generation of digital data through various processes, as well as the sourcing, collation, integration, and distribution of existing digital data. Key initiatives under FinBIF include the digitization of collections, the development of data systems for collections Kotka (https://biss.pensoft.net/article/37179/) and observations (https://biss.pensoft.net/article/39150/), and the establishment of a national DNA barcode reference library. FinBIF manages data types such as verbal species descriptions (which include drawings, pictures, and other media types), biological taxonomy, scientific collection specimens, opportunistic systematic and event-based observations, and DNA barcodes. It employs a unified IT architecture to manage data flows, delivers services through a single online portal, fosters collaboration under a cohesive umbrella concept, and articulates development visions under a unified brand. The portal Laji.fi serves as the entry point to this harmonized open data ecosystem. FinBIF's portal is accessible in Finnish, Swedish, and English. Data intended for restricted use are made available to authorities through a separate portal, while open data are also shared with international systems, such as GBIF.