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TopFIND is a protein-centric database for the annotation of protein termini currently in its third version. Non-canonical protein termini can be the result of multiple different biological processes, including pre-translational processes such as alternative splicing and alternative translation initiation or post-translational protein processing by proteases that cleave proteases as part of protein maturation or as a regulatory modification. Accordingly, protein termini evidence in TopFIND is inferred from other databases such as ENSEMBL transcripts, TISdb for alternative translation initiation, MEROPS for protein cleavage by proteases, and UniProt for canonical and protein isoform start sites.
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This purpose of this repository is to share Ontario's government data sets online to increase transparency and accountability. We're adding to the hundreds of records we’ve released so far to create an inventory of known government data. Data will either be open, restricted, under review or in the process of being made open, depending on the sensitivity of the information.