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Found 36 result(s)
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bonndata is the institutional, FAIR-aligned and curated, cross-disciplinary research data repository for the publication of research data for all researchers at the University of Bonn. The repository is fully embedded into the University IT and Data Center and curated by the Research Data Service Center (https://www.forschungsdaten.uni-bonn.de/en). The software that bonndata is based on is the open source software Dataverse (https://dataverse.org)
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An Open Science resource that promotes scientific research and discovery in neurological diseases and accelerates the development of new treatments. It includes a growing collection of biospecimens, longitudinal clinical and neuropsychiatric information, imaging and genetic data from patients with neurological disease as well as healthy controls.
The BigBrain Project repository contains data from BigBrain: A high-resolution, 3D model of a human post-mortem brain, which was obtained in accordance with ethical requirements of the University of Düsseldorf. The brain of a 65-year-old body donor was sectioned, stained for cell bodies, scanned at very high resolution, and then digitally reconstructed in 3D. The full dataset of images, volumes, and surfaces are available for download on the project's ftp site, while a subset of files offering different spatial resolutions can be accessed via LORIS. The web-based 3D interactive atlas viewer is capable of displaying very large brain volumes, including oblique slicing, a whole brain overview, surface meshes, and maps. It enables navigating the BigBrain in 3D, exploring the growing set of highly detailed maps for cortical layers and cytoarchitectonic areas, and finding related neuroscience data.
Brain Analysis Library of Spatial maps and Atlases (BALSA) is a database for hosting and sharing neuroimaging and neuroanatomical datasets for human and primate species. BALSA houses curated, user-created Study datasets, extensively analyzed neuroimaging data associated with published figures and Reference datasets mapped to brain atlas surfaces and volumes in human and nonhuman primates as a general resource (e.g., published cortical parcellations).
Reference anatomies of the brain and corresponding atlases play a central role in experimental neuroimaging workflows and are the foundation for reporting standardized results. The choice of such references —i.e., templates— and atlases is one relevant source of methodological variability across studies, which has recently been brought to attention as an important challenge to reproducibility in neuroscience. TemplateFlow is a publicly available framework for human and nonhuman brain models. The framework combines an open database with software for access, management, and vetting, allowing scientists to distribute their resources under FAIR —findable, accessible, interoperable, reusable— principles. TemplateFlow supports a multifaceted insight into brains across species, and enables multiverse analyses testing whether results generalize across standard references, scales, and in the long term, species, thereby contributing to increasing the reliability of neuroimaging results.
The Pennsieve platform is a cloud-based scientific data management platform focused on integrating complex datasets, fostering collaboration and publishing scientific data according to all FAIR principles of data sharing. The platform is developed to enable individual labs, consortiums, or inter-institutional projects to manage, share and curate data in a secure cloud-based environment and to integrate complex metadata associated with scientific files into a high-quality interconnected data ecosystem. The platform is used as the backend for a number of public repositories including the NIH SPARC Portal and Pennsieve Discover repositories. It supports flexible metadata schemas and a large number of scientific file-formats and modalities.
The ENCODE Encyclopedia organizes the most salient analysis products into annotations, and provides tools to search and visualize them. The Encyclopedia has two levels of annotations: Integrative-level annotations integrate multiple types of experimental data and ground level annotations. Ground-level annotations are derived directly from the experimental data, typically produced by uniform processing pipelines.
A place where researchers can publicly store and share unthresholded statistical maps, parcellations, and atlases produced by MRI and PET studies.
Brainlife promotes engagement and education in reproducible neuroscience. We do this by providing an online platform where users can publish code (Apps), Data, and make it "alive" by integragrate various HPC and cloud computing resources to run those Apps. Brainlife also provide mechanisms to publish all research assets associated with a scientific project (data and analyses) embedded in a cloud computing environment and referenced by a single digital-object-identifier (DOI). The platform is unique because of its focus on supporting scientific reproducibility beyond open code and open data, by providing fundamental smart mechanisms for what we refer to as “Open Services.”
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<<<!!!<<< Significantly expanded physical protein interaction database is now available as IID - Integrated Interactions Database. It is 74% larger than I2D and includes annotation of tissue-specific interactions across 30 tissues. https://www.re3data.org/repository/r3d100010675 >>>!!!>>>
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FlyCircuit is a public database for online archiving, cell type inventory, browsing, searching, analysis and 3D visualization of individual neurons in the Drosophila brain. The FlyCircuit Database currently contains about 30,000 high resolution 3D brain neural images of the drosophila fruit fly brain that are combined into a neural circuitry network that researchers can use as a blueprint to further explore how the brain of a fruit fly processes external sensory signals (i.e. how vision, hearing, and smell are transmitted to the central nerve system).
The Allen Brain Atlas provides a unique online public resource integrating extensive gene expression data, connectivity data and neuroanatomical information with powerful search and viewing tools for the adult and developing brain in mouse, human and non-human primate
The PAIN Repository is a recently funded NIH initiative, which has two components: an archive for already collected imaging data (Archived Repository), and a repository for structural and functional brain images and metadata acquired prospectively using standardized acquisition parameters (Standardized Repository) in healthy control subjects and patients with different types of chronic pain. The PAIN Repository provides the infrastructure for storage of standardized resting state functional, diffusion tensor imaging and structural brain imaging data and associated biological, physiological and behavioral metadata from multiple scanning sites, and provides tools to facilitate analysis of the resulting comprehensive data sets.
The goal of the NeuroElectro Project is to extract information about the electrophysiological properties (e.g. resting membrane potentials and membrane time constants) of diverse neuron types from the existing literature and place it into a centralized database.
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<<<!!!<<< This repository is no longer available. >>>!!!>>> A human interactome map. The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins. These macromolecules regulate the vast majority of cellular processes by their ability to communicate with each other and to assemble into larger functional units. Therefore, the systematic analysis of protein-protein interactions is fundamental for the understanding of protein function, cellular processes and, ultimately, the complexity of life. Moreover, interactome maps are particularly needed to link new proteins to disease pathways and the identification of novel drug targets.
The Brain Transcriptome Database (BrainTx) project aims to create an integrated platform to visualize and analyze our original transcriptome data and publicly accessible transcriptome data related to the genetics that underlie the development, function, and dysfunction stages and states of the brain.
Neuroimaging Tools and Resources Collaboratory (NITRC) is currently a free one-stop-shop environment for science researchers that need resources such as neuroimaging analysis software, publicly available data sets, and computing power. Since its debut in 2007, NITRC has helped the neuroscience community to use software and data produced from research that, before NITRC, was routinely lost or disregarded, to make further discoveries. NITRC provides free access to data and enables pay-per-use cloud-based access to unlimited computing power, enabling worldwide scientific collaboration with minimal startup and cost. With NITRC and its components—the Resources Registry (NITRC-R), Image Repository (NITRC-IR), and Computational Environment (NITRC-CE)—a researcher can obtain pilot or proof-of-concept data to validate a hypothesis for a few dollars.
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Oral Cancer Gene Database is an initiative of the Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai. The present database, version II, consists of 374 genes. It is developed as a user friendly site that would provide the scientist, information and external links from one place. The database is accessed through a list of all genes, and Keyword Search using gene name or gene symbol, chromosomal location, CGH (in %), and molecular weight. Interaction Network shows the interaction between genes for particular biological processes and molecular functions.
Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.