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Found 559 result(s)

DEPOD

DEPhOsphorylation Database

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DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.

TwinsUK

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The TwinsUK resource is the biggest UK adult twin registry of 14.000 twins used to study the genetic and environmental aetiology of age related complex traits and diseases.

TanDEM-X ISDC

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<<<!!!<<< This page is no longer available. >>>!!!>>>

Science3D

Science 3D

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<<<!!!<<< This repository is no longer available. This record is out-dated >>>!!!>>> Science3D is an Open Access project to archive and curate scientific data and make them available to everyone interested in scientific endeavours. Science3D focusses mainly on 3D tomography data from biological samples, simply because theses object make it comparably easy to understand the concepts and techniques. The data come primarily from the imaging beamlines of the Helmholtz Center Geesthacht (HZG), which make use of the uniquely bright and coherent X-rays of the Petra3 synchrotron. Petra3 - like many other photon and neutron sources in Europe and World-wide - is a fantastic instrument to investigate the microscopic detail of matter and organisms. The experiments at photon science beamlines hence provide unique insights into all kind of scientific fields, ranging from medical applications to plasma physics. The success of these experiments demands enormous efforts of the scientists and quite some investments

Project Achilles

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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/

ALSoD

ALS Online Database

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ALSoD is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene to a multigene ALS bioinformatics repository and analytical instrument combining genotype, phenotype, and geographical information with associated analysis tools. These include a comparison tool to evaluate genes side by side or jointly with user configurable features, a pathogenicity prediction tool using a combination of computational approaches to distinguish variants with nonfunctional characteristics from disease-associated mutations with more dangerous consequences, and a credibility tool to enable ALS researchers to objectively assess the evidence for gene causation in ALS. Furthermore, integration of external tools, systems for feedback, annotation by users, and two-way links to collaborators hosting complementary databases further enhance the functionality of ALSoD.

MRC National Survey of Health and Development

NSHD

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The MRC National Survey of Health and Development 1946 (NSHD) was the first ever British birth cohort study. It has collected information from birth to the current day on the health and life circumstances of five and a half thousand men and women born during a week in March 1946 throughout England, Wales, and Scotland. The study explores differences in child development by factors like social class, biological factors, health and education. Due to the length of the study it has developed into a study of ageing.

Digitale Sammlungen

Digital Collections

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The Digital Collections include digitized manuscripts, prints, music, maps, photographs, newspapers and magazines from the rich holdings of the Bayerische Staatsbibliothek. Almost the entire content (>98%) is available for download for research purposes or via IIIF APIs, including all available OCR data.

Harvard Medical School, Library of Integrated Network-Based Cellular Signatures Database

HMS, LINCS database

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The Database contains all publicly available HMS LINCS datasets and information for each dataset about experimental reagents (small molecule perturbagens, cells, antibodies, and proteins) and experimental and data analysis protocols.

SedDB

Integrated Data Management for Sediment Geochemistry

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<<<!!!<<< This repository is no longer available. >>>!!!>>> SedDB complements current geological data systems (PetDB, EarthChem, NavDat and GEOROC) with an integrated compilation of geochemistry of marine and continental sediments. Notice: Content of SedDB has been static since 2014 and will not be updated until further notice.

GNSS - ISDC

Global Navigation Satellite Systems - Information System and Data Center

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The term GNSS (Global Navigation Satellite Systems) comprises the different navigation satellite systems like GPS, GLONAS and the future Galileo as well as rawdata from GNSS microwave receivers and processed or derived higher level products and required auxiliary data. The results of the GZF GNSS technology based projects are used as contribution for maintaining and studying the Earth rotational behavior and the global terrestial reference frame, for studying neotectonic processes along plate boundaries and the interior of plates and as input to short term weather forecasting and atmosphere/climate research. Currently only selected products like observation data, navigation data (ephemeriden), meteorological data as well as quality data with a limited spatial coverage are provided by the GNSS ISDC.

Alternative Fuels Data Center

AFDC

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The Alternative Fuels Data Center (AFDC) is a comprehensive clearinghouse of information about advanced transportation technologies. The AFDC offers transportation decision makers unbiased information, data, and tools related to the deployment of alternative fuels and advanced vehicles. The AFDC launched in 1991 in response to the Alternative Motor Fuels Act of 1988 and the Clean Air Act Amendments of 1990. It originally served as a repository for alternative fuel performance data. The AFDC has since evolved to offer a broad array of information resources that support efforts to reduce petroleum use in transportation. The AFDC serves Clean Cities stakeholders, fleets regulated by the Energy Policy Act, businesses, policymakers, government agencies, and the general public.

IOWDB

Die ozeanographische Datenbank des IOW

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The IOWDB was designed for the particular requirements of the Leibniz Institute for Baltic Sea Research. It is aimed at the management of historical and recent measurement of the IOW (to some extend of other data, too) and to provide them in a user-friendly way via the research tool ODIN (Oceanographic Database research with Interactive Navigation).

GGOS ICGEM

Global Geodetic Observing System at GFZ International Center for Global Gravity Field Models

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<<<!!!<<< Duplicate to https://www.re3data.org/repository/r3d100011116 , this entry is no longer maintained >>>!!!>>> GGOS is the Global Geodetic Observing System of the International Association of Geodesy (IAG). It provides observations of the three fundamental geodetic observables and their variations, that is, the Earth's shape, the Earth's gravity field and the Earth's rotational motion. GGOS integrates different geodetic techniques, different models, different approaches in order to ensure a long-term, precise monitoring of the geodetic observables in agreement with the Integrated Global Observing Strategy (IGOS). GGOS provides the observational basis to maintain a stable, accurate and global reference frame and in this function is crucial for all Earth observation and many practical applications.

GGSP - ISDC

Galileo Geodetic Service Provider - Information System and Data Center

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The main function of the GGSP (Galileo Geodetic Service Provider) is to provide a terrestrial reference frame, in the broadest sense of the word, to both the Galileo Core System (GCS) as well as to the Galileo User Segment (all Galileo users). This implies that the GGSP should enable all users of the Galileo System, including the most demanding ones, to access and realise the GTRF with the precision required for their specific application. Furthermore, the GGSP must ensure the proper interfaces to all users of the GTRF, especially the geodetic and scientific user groups. In addition the GGSP must ensure the adherence to the defined standards of all its products. Last but not least the GGSP will play a key role to create awareness of the GTRF and educate users in the usage and realisation of the GTRF.

The World Data Center for Remote Sensing of the Atmosphere

WDC-RSAT

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The World Data Center for Remote Sensing of the Atmosphere, WDC-RSAT, offers scientists and the general public free access (in the sense of a “one-stop shop”) to a continuously growing collection of atmosphere-related satellite-based data sets (ranging from raw to value added data), information products and services. Focus is on atmospheric trace gases, aerosols, dynamics, radiation, and cloud physical parameters. Complementary information and data on surface parameters (e.g. vegetation index, surface temperatures) is also provided. This is achieved either by giving access to data stored at the data center or by acting as a portal containing links to other providers.

GRACE ISDC

Gravity Recovery and Climate Experiment

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The twin GRACE satellites were launched on March 17, 2002. Since that time, the GRACE Science Data System (SDS) has produced and distributed estimates of the Earth gravity field on an ongoing basis. These estimates, in conjunction with other data and models, have provided observations of terrestrial water storage changes, ice-mass variations, ocean bottom pressure changes and sea-level variations. This portal, together with PODAAC, is responsible for the distribution of the data and documentation for the GRACE project.

CHAMP

Challenging Minisatellite Payload

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CHAMP (CHAllenging Minisatellite Payload) is a German small satellite mission for geoscientific and atmospheric research and applications, managed by GFZ. With its highly precise, multifunctional and complementary payload elements (magnetometer, accelerometer, star sensor, GPS receiver, laser retro reflector, ion drift meter) and its orbit characteristics (near polar, low altitude, long duration) CHAMP will generate for the first time simultaneously highly precise gravity and magnetic field measurements over a 5 years period. This will allow to detect besides the spatial variations of both fields also their variability with time. The CHAMP mission had opened a new era in geopotential research and had become a significant contributor to the Decade of Geopotentials. In addition with the radio occultation measurements onboard the spacecraft and the infrastructure developed on ground, CHAMP had become a pilot mission for the pre-operational use of space-borne GPS observations for atmospheric and ionospheric research and applications in weather prediction and space weather monitoring. End of the mission of CHAMP was at September 19 2010, after ten years, two month and four days, after 58277 orbits.

MIPAS/Envisat Observations of Polar Stratospheric Clouds

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This data repository provides access to the climatology of polar stratospheric clouds (PSC) observations of Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) onboard the Envisat satellite of the European Space Agency (ESA). The MIPAS instrument operated from July 2002 until April 2012. The infrared limb emission measurements provide a unique dataset of day and night observations of polar stratospheric clouds (PSCs) up to both poles.

Jülich ObservatorY for Cloud Evolution - Core Facility

formerly: JOYCE

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The Jülich Observatory for Cloud Evolution (JOYCE) operates ground-based active and passive remote sensing instruments for cloud and precipitation observations. ​JOYCE is based on a long-term successful collaboration between the University of Cologne, the University of Bonn and the Research Centre Jülich. Since 2017 JOYCE is transformed into a Core Facility (JOYCE - CF) funded by the DFG (Deutsche Forschungsgemeinschaft) with the aim of high quality radar and passive microwave observations of the atmosphere. JOYCE will serve as a reference center for best practices in data acquisition, storage and distribution. JOYCE instrumentation aims to observe spatial and temporal variability of atmospheric water cycle variables.

European Zebrafish Resource Center

EZRC

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The EZRC at KIT houses the largest experimental fish facility in Europe with a capacity of more than 300,000 fish. Zebrafish stocks are maintained mostly as frozen sperm. Frequently requested lines are also kept alive as well as a selection of wildtype strains. Several thousand mutations in protein coding genes generated by TILLING in the Stemple lab of the Sanger Centre, Hinxton, UK and lines generated by ENU mutagenesis by the Nüsslein-Volhard lab in addition to transgenic lines and mutants generated by KIT groups or brought in through collaborations. We also accept submissions on an individual basis and ship fish upon request to PIs in Europe and elsewhere. EZRC also provides screening services and technologies such as imaging and high-throughput sequencing. Key areas include automation of embryo handling and automated image acquisition and processing. Our platform also involves the development of novel microscopy techniques (e.g. SPIM, DSLM, robotic macroscope) to permit high-resolution, real-time imaging in 4D. By association with the ComPlat platform, we can support also chemical screens and offer libraries with up to 20,000 compounds in total for external users. As another service to the community the EZRC provides plasmids (cDNAs, transgenes, Talen, Crispr/cas9) maintained by the Helmholtz repository of Bioparts (HERBI) to the scientific community. In addition the fish facility keeps a range of medaka stocks, maintained by the Loosli group.

Reanalysis Tropopause Data Repository

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This data repository provides access to tropopause parameters estimated from meteorological reanalyses. The tropopause data sets provided on this web site have been created using meteorological reanalyses distributed by the European Centre for Medium-Range Weather Forecasts (ECMWF), the National Aeronautics and Space Administration (NASA), the National Center for Atmospheric Research (NCAR), and the National Centers for Atmospheric Prediction (NCEP). Currently, the repository covers ERA-Interim, MERRA-2, and the NCEP/NCAR Reanalysis 1 for the time period from 2000 to 2018 and ERA5 from 2009 to 2018. The tropopause data files provide geopotential height, pressure, temperature, and water vapor volume mixing ratio for the WMO 1st and 2nd tropopause, the cold point, and the dynamical tropopause.

PAC - Archiving Platform CINES

PAC - Plateforme d'Archivage au CINES

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CINES is the French national long-term preservation service provider for Higher Education and Research: more than 20 institutions (universities, librairies, labs) archive their digital heritage at CINES so that it's preserved over time in a secure, dedicated environment. This includes documents such as PhD theses or publications, digitized ancient/rare books, satellite imagery, 3D/vidéos/image galleries, datasets, etc.

AIRS/Aqua Observations of Gravity Waves

Atmospheric Infrared Sounder / Aqua Observations of Gravity Waves

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This data repository provides access to gravity wave observations of the Atmospheric Infrared Sounder (AIRS) aboard NASA's Aqua satellite. Information on stratospheric gravity wave activity is derived from radiance measurements in the 4.3 and 15 micron CO2 fundamental bands. The repository provides browse images and netCDF data files for the years 2002 to 2017 and is frequently updated.

Data Portal of the Alfred Wegener Institute

including: AWI EXPEDITION

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<<<!!!<<< This repository is no longer available. >>>!!!>>> This page is not longer active, please use www.marine-data.de instead. Our data portal data.awi.de offers an integrative one-stop shop framework for discovering AWI research platforms including devices and sensors, tracklines, field reports, peer-reviewed publications, GIS products and mostly important data and data products archived in PANGAEA.