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The Sloan Digital Sky Survey (SDSS) is one of the most ambitious and influential surveys in the history of astronomy. Over eight years of operations (SDSS-I, 2000-2005; SDSS-II, 2005-2008; SDSS-III 2008-2014; SDSS-IV 2013 ongoing), it obtained deep, multi-color images covering more than a quarter of the sky and created 3-dimensional maps containing more than 930,000 galaxies and more than 120,000 quasars. DSS-IV is managed by the Astrophysical Research Consortium for the Participating Institutions of the SDSS Collaboration including the Carnegie Institution for Science, Carnegie Mellon University, the Chilean Participation Group, Harvard-Smithsonian Center for Astrophysics, Instituto de Astrofísica de Canarias, The Johns Hopkins University, Kavli Institute for the Physics and Mathematics of the Universe (IPMU) / University of Tokyo, Lawrence Berkeley National Laboratory, Leibniz Institut für Astrophysik Potsdam (AIP), Max-Planck-Institut für Astrophysik (MPA Garching), Max-Planck-Institut für Extraterrestrische Physik (MPE), Max-Planck-Institut für Astronomie (MPIA Heidelberg), National Astronomical Observatory of China, New Mexico State University, New York University, The Ohio State University, Pennsylvania State University, Shanghai Astronomical Observatory, United Kingdom Participation Group, Universidad Nacional Autónoma de México, University of Arizona, University of Colorado Boulder, University of Portsmouth, University of Utah, University of Washington, University of Wisconsin, Vanderbilt University, and Yale University.
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During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome (spindle pole in budding yeast), kinetochore/centromere, cleavage furrow/midbody (related or homolog structures in plants and budding yeast called as phragmoplast and bud neck, respectively), telomere and spindle spatially and temporally. These sub-cellular regions play important roles in various biological processes. In this work, we have collected all proteins identified to be localized on kinetochore, centrosome, midbody, telomere and spindle from two fungi (S. cerevisiae and S. pombe) and five animals, including C. elegans, D. melanogaster, X. laevis, M. musculus and H. sapiens based on the rationale of "Seeing is believing" (Bloom K et al., 2005). Through ortholog searches, the proteins potentially localized at these sub-cellular regions were detected in 144 eukaryotes. Then the integrated and searchable database MiCroKiTS - Midbody, Centrosome, Kinetochore, Telomere and Spindle has been established.
The NCEP/NCAR Reanalysis Project is a joint project between the National Centers for Environmental Prediction (NCEP, formerly "NMC") and the National Center for Atmospheric Research (NCAR). The goal of this joint effort is to produce new atmospheric analyses using historical data (1948 onwards) and as well to produce analyses of the current atmospheric state (Climate Data Assimilation System, CDAS).
ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data). The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.