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Found 178 result(s)

European Zebrafish Resource Center

EZRC

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The EZRC at KIT houses the largest experimental fish facility in Europe with a capacity of more than 300,000 fish. Zebrafish stocks are maintained mostly as frozen sperm. Frequently requested lines are also kept alive as well as a selection of wildtype strains. Several thousand mutations in protein coding genes generated by TILLING in the Stemple lab of the Sanger Centre, Hinxton, UK and lines generated by ENU mutagenesis by the Nüsslein-Volhard lab in addition to transgenic lines and mutants generated by KIT groups or brought in through collaborations. We also accept submissions on an individual basis and ship fish upon request to PIs in Europe and elsewhere. EZRC also provides screening services and technologies such as imaging and high-throughput sequencing. Key areas include automation of embryo handling and automated image acquisition and processing. Our platform also involves the development of novel microscopy techniques (e.g. SPIM, DSLM, robotic macroscope) to permit high-resolution, real-time imaging in 4D. By association with the ComPlat platform, we can support also chemical screens and offer libraries with up to 20,000 compounds in total for external users. As another service to the community the EZRC provides plasmids (cDNAs, transgenes, Talen, Crispr/cas9) maintained by the Helmholtz repository of Bioparts (HERBI) to the scientific community. In addition the fish facility keeps a range of medaka stocks, maintained by the Loosli group.

PANGAEA

Data Publisher for Earth and Environmental Science

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PANGAEA - Data Publisher for Earth & Environmental Sciences has an almost 30-year history as an open-access library for archiving, publishing, and disseminating georeferenced data from the Earth, environmental, and biodiversity sciences. Originally evolving from a database for sediment cores, it is operated as a joint facility of the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) and the Center for Marine Environmental Sciences (MARUM) at the University of Bremen. PANGAEA holds a mandate from the World Meteorological Organization (WMO) and is accredited as a World Radiation Monitoring Center (WRMC). It was further accredited as a World Data Center by the International Council for Science (ICS) in 2001 and has been certified with the Core Trust Seal since 2019. The successful cooperation between PANGAEA and the publishing industry along with the correspondent technical implementation enables the cross-referencing of scientific publications and datasets archived as supplements to these publications. PANGAEA is the recommended data repository of numerous international scientific journals.

Collaborative Climate Community Data and Processing Grid

C3Grid

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<<<!!!<<< This repository is no longer available. >>>!!!>>> C3-Grid is an ALREADY FINISHED project within D-Grid, the initiative to promote a grid-based e-Science framework in Germany. The goal of C3-Grid is to support the workflow of Earth system researchers. A grid infrastructure will be implemented that allows efficient distributed data processing and inter-institutional data exchange. Aim of the effort was to develop an infrastructure for uniform access to heterogeneous data and distributed data processing. The work was structured in two projects funded by the Federal Ministry of Education and Research. The first project was part of the D-Grid initiative and explored the potential of grid technology for climate research and developed a prototype infrastructure. Details about the C3Grid architecture are described in “Earth System Modelling – Volume 6”. In the second phase "C3Grid - INAD: Towards an Infrastructure for General Access to Climate Data" this infrastructure was improved especially with respect to interoperability to Earth System Grid Federation (ESGF). Further the portfolio of available diagnostic workflows was expanded. These workflows can be re-used now in adjacent infrastructures MiKlip Evaluation Tool (http://www.fona-miklip.de/en/index.php) and as Web Processes within the Birdhouse Framework (http://bird-house.github.io/). The Birdhouse Framework is now funded as part of the European Copernicus Climate Change Service (https://climate.copernicus.eu/) managed by ECMWF and will be extended to provide scalable processing services for ESGF hosted data at DKRZ as well as IPSL and BADC.