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The Cancer Immunome Database (TCIA) provides results of comprehensive immunogenomic analyses of next generation sequencing data (NGS) data for 20 solid cancers from The Cancer Genome Atlas (TCGA) and other datasource. The Cancer Immunome Atlas (TCIA) was developed and is maintained at the Division of Bioinformatics (ICBI). The database can be queried for the gene expression of specific immune-related gene sets, cellular composition of immune infiltrates (characterized using gene set enrichment analyses and deconvolution), neoantigens and cancer-germline antigens, HLA types, and tumor heterogeneity (estimated from cancer cell fractions). Moreover it provides survival analyses for different types immunological parameters. TCIA will be constantly updated with new data and results.
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The Austrian NeuroCloud (ANC) is a FAIR-enabling platform for sustainable research data management in Cognitive Neuroscience. Most of the offered research data is restricted, the publicly available datasets can be seen under https://data.anc.plus.ac.at/explore The ANC offers tools and services to archive, manage, and share neurocognitive data flexibly and according to community standards. Scientists have full control over what they share (e.g., full original datasets or data derivatives), how they share it (by choosing from a selection of licensing models), and with whom (e.g., by using the ANC’s adjustable User Agreement templates). The ANC provides persistent DOIs for data releases and operates in accordance with European GDPR. Moreover, the ANC fully supports the mission of the EOSC and is committed to the EU’s open science policy, legal standards, and best open science practices. Accordingly, the ANC aspires to facilitate FAIR data operations along the entire data lifecycle, actively supporting the ongoing shift in research culture towards increased transparency, data reusability, and result reproducibility.
mzCloud is an extensively curated database of high-resolution tandem mass spectra that are arranged into spectral trees. MS/MS and multi-stage MSn spectra were acquired at various collision energies, precursor m/z, and isolation widths using Collision-induced dissociation (CID) and Higher-energy collisional dissociation (HCD). Each raw mass spectrum was filtered and recalibrated giving rise to additional filtered and recalibrated spectral trees that are fully searchable. Besides the experimental and processed data, each database record contains the compound name with synonyms, the chemical structure, computationally and manually annotated fragments (peaks), identified adducts and multiply charged ions, molecular formulas, predicted precursor structures, detailed experimental information, peak accuracies, mass resolution, InChi, InChiKey, and other identifiers. mzCloud is a fully searchable library that allows spectra searches, tree searches, structure and substructure searches, monoisotopic mass searches, peak (m/z) searches, precursor searches, and name searches. mzCloud is free and available for public use online.