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Found 356 result(s)

The Microbial Protein Interaction Database

MPIDB

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>>>!!!<<< as stated 2017-06-09 MPIDB is no longer available under URL http://www.jcvi.org/mpidb/about.php >>>!!!<<< The microbial protein interaction database (MPIDB) aims to collect and provide all known physical microbial interactions. Currently, 24,295 experimentally determined interactions among proteins of 250 bacterial species/strains can be browsed and downloaded. These microbial interactions have been manually curated from the literature or imported from other databases (IntAct, DIP, BIND, MINT) and are linked to 26,578 experimental evidences (PubMed ID, PSI-MI methods). In contrast to these databases, interactions in MPIDB are further supported by 68,346 additional evidences based on interaction conservation, protein complex membership, and 3D domain contacts (iPfam, 3did). We do not include (spoke/matrix) binary interactions infered from pull-down experiments.

Fungal Genetics Stock Center

FGSC

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The Fungal Genetics Stock Center has preserved and distributed strains of genetically characterized fungi since 1960. The collection includes over 20,000 accessioned strains of classical and genetically engineered mutants of key model, human, and plant pathogenic fungi. These materials are distributed as living stocks to researchers around the world.

Earth System Grid Federation

ESGF

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The Earth System Grid Federation (ESGF) is an international collaboration with a current focus on serving the World Climate Research Programme's (WCRP) Coupled Model Intercomparison Project (CMIP) and supporting climate and environmental science in general. Data is searchable and available for download at the Federated ESGF-CoG Nodes https://esgf.llnl.gov/nodes.html

CaltechLabNotes

California Institute of Technology LabNotes

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Lab Notes Online presents historic scientific data from the Caltech Archives' collections in digital facsimile. Beginning in the fall of 2008, the first publication in the series is Robert A. Millikan's notebooks for his oil drop experiments to measure the charge of the electron, dating from October 1911 to April 1912. Other laboratory, field, or research notes will be added to the archive over time.

Cancer Genomics Hub

CGHub

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>>>>!!!!<<<< The Cancer Genomics Hub mission is now completed. The Cancer Genomics Hub was established in August 2011 to provide a repository to The Cancer Genome Atlas, the childhood cancer initiative Therapeutically Applicable Research to Generate Effective Treatments and the Cancer Genome Characterization Initiative. CGHub rapidly grew to be the largest database of cancer genomes in the world, storing more than 2.5 petabytes of data and serving downloads of nearly 3 petabytes per month. As the central repository for the foundational genome files, CGHub streamlined team science efforts as data became as easy to obtain as downloading from a hard drive. The convenient access to Big Data, and the collaborations that CGHub made possible, are now essential to cancer research. That work continues at the NCI's Genomic Data Commons. All files previously stored at CGHub can be found there. The Website for the Genomic Data Commons is here: https://gdc.nci.nih.gov/ >>>>!!!!<<<< The Cancer Genomics Hub (CGHub) is a secure repository for storing, cataloging, and accessing cancer genome sequences, alignments, and mutation information from the Cancer Genome Atlas (TCGA) consortium and related projects. Access to CGHub Data: All researchers using CGHub must meet the access and use criteria established by the National Institutes of Health (NIH) to ensure the privacy, security, and integrity of participant data. CGHub also hosts some publicly available data, in particular data from the Cancer Cell Line Encyclopedia. All metadata is publicly available and the catalog of metadata and associated BAMs can be explored using the CGHub Data Browser.

FLOSSmole

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FLOSSmole is a collaborative collection of free, libre, and open source software (FLOSS) data. FLOSSmole contains nearly 1 TB of data covering the period 2004 until now, about more than 500,000 different open source projects.

The Paleobiology Database

PaleoDB

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The Paleobiology Database (PaleoBioDB) is a non-governmental, non-profit public resource for paleontological data. It has been organized and operated by a multi-disciplinary, multi-institutional, international group of paleobiological researchers. Its purpose is to provide global, collection-based occurrence and taxonomic data for organisms of all geological ages, as well data services to allow easy access to data for independent development of analytical tools, visualization software, and applications of all types. The Database’s broader goal is to encourage and enable data-driven collaborative efforts that address large-scale paleobiological questions.

UniGene

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<<<!!!<<< This repository is no longer available>>>!!!>>>. Although the web pages are no longer available, you will still be able to download the final UniGene builds as static content from the FTP site https://ftp.ncbi.nlm.nih.gov/repository/UniGene/. You will also be able to match UniGene cluster numbers to Gene records by searching Gene with UniGene cluster numbers. For best results, restrict to the “UniGene Cluster Number” field rather than all fields in Gene. For example, a search with Mm.2108[UniGene Cluster Number] finds the mouse transthyretin Gene record (Ttr). You can use the advanced search page https://www.ncbi.nlm.nih.gov/gene/advanced to help construct these searches. Keep in mind that the Gene record contains selected Reference Sequences and GenBank mRNA sequences rather than the larger set of expressed sequences in the UniGene cluster.

USGS National Water Information System

NWIS

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Central data management of the USGS for water data that provides access to water-resources data collected at approximately 1.5 million sites in all 50 States, the District of Columbia, Puerto Rico, the Virgin Islands, Guam, American Samoa and the Commonwealth of the Northern Mariana Islands. Includes data on water use and quality, groundwater, and surface water.

National Virtual Observatory

NVO

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<<<!!!>>> NVO - National Virtual Observatory is closed now <<<!!! >>> The National Virtual Observatory (NVO) was the predecessor of the VAO. It was a research project aimed at developing the technologies that would be used to build an operational Virtual Observatory. With the NVO era now over, a new organization has been funded in its place, with the explicit goal of creating useful tools for users to take advantage of the groundwork laid by the NVO. To carry on with the NVO's goals, we hereby introduce you to the Virtual Astronomical Observatory http://www.usvao.org/

Berkeley Drosophila Genome Project insitu

BDGP insitu homepage

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In early 2010 we updated the site to facilitate more rapid transfer of our data to the public database and focus our efforts on the core mission of providing expression pattern images to the research community. The original database https://www.fruitfly.org/index.html reproduced functions available on FlyBase, complicating our updates by the requirement to re-synchronize with FlyBase updates. Our expression reports on the new site still link to FlyBase gene reports, but we no longer reproduce FlyBase functions and therefore can update expression data on an ongoing basis instead of more infrequent major releases. All the functions relating to the expression patterns remain and we soon will add an option to search expression patterns by image similarity, in addition to annotation term searches. In a transitional phase we will leave both the old and the new sites up, but the newer data (post Release 2) will appear only on the new website. We welcome any feedback or requests for additional features. - The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community.

ScienceBase USGS

ScienceBase catalog

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ScienceBase provides access to aggregated information derived from many data and information domains, including feeds from existing data systems, metadata catalogs, and scientists contributing new and original content. ScienceBase architecture is designed to help science teams and data practitioners centralize their data and information resources to create a foundation needed for their work. ScienceBase, both original software and engineered components, is released as an open source project to promote involvement from the larger scientific programming community both inside and outside the USGS.

Nasa's Data Portal

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DATA.NASA.GOV is NASA's clearinghouse site for open-data provided to the public. Tens of thousands of datasets are available for you. This site is a continually growing catalog of publicly available NASA Datasets, APIs, Visualizations, and more.

USGODAE Argo GDAC Data Browser

US Global Ocean Data Assimilation Experiment Argo Global Data Assembly Center Data Browser

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!!! <<< the repository is offline, please use: https://www.re3data.org/repository/r3d100011650 >>> !!! The USGODAE Project consists of United States academic, government and military researchers working to improve assimilative ocean modeling as part of the International GODAE Project. GODAE hopes to develop a global system of observations, communications, modeling and assimilation, that will deliver regular, comprehensive information on the state of the oceans, in a way that will promote and engender wide utility and availability of this resource for maximum benefit to the community. The USGODAE Argo GDAC is currently operational, serving daily data from the following national DACs: Australia (CSIRO), Canada (MEDS), China (2: CSIO and NMDIS), France (Coriolis), India (INCOIS), Japan (JMA), Korea (2: KMA and Kordi), UK (BODC), and US (AOML).

Avian Knowledge Network

AKN

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The Avian Knowledge Network (AKN) is an international network of governmental and non-governmental institutions and individuals linking avian conservation, monitoring and science through efficient data management and coordinated development of useful solutions using best-science practices based on the data.

OpenWorm

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OpenWorm aims to build the first comprehensive computational model of the Caenorhabditis elegans (C. elegans), a microscopic roundworm. With only a thousand cells, it solves basic problems such as feeding, mate-finding and predator avoidance. Despite being extremely well studied in biology, this organism still eludes a deep, principled understanding of its biology. We are using a bottom-up approach, aimed at observing the worm behaviour emerge from a simulation of data derived from scientific experiments carried out over the past decade. To do so we are incorporating the data available in the scientific community into software models. We are engineering Geppetto and Sibernetic, open-source simulation platforms, to be able to run these different models in concert. We are also forging new collaborations with universities and research institutes to collect data that fill in the gaps All the code we produce in the OpenWorm project is Open Source and available on GitHub.

Gulf Coast Repository

GCR

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The International Ocean Discovery Program’s (IODP) Gulf Coast Repository (GCR) is located in the Research Park on the Texas A&M University campus in College Station, Texas. This repository stores DSDP, ODP, and IODP cores from the Pacific Ocean, the Caribbean Sea and Gulf of Mexico, and the Southern Ocean. A satellite repository at Rutgers University houses New Jersey/Delaware land cores 150X and 174AX.

NeuroElectro

organizing information on cellular neurophysiology

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The goal of the NeuroElectro Project is to extract information about the electrophysiological properties (e.g. resting membrane potentials and membrane time constants) of diverse neuron types from the existing literature and place it into a centralized database.

International HapMap Project

国际人类基因组单体型图计划

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<<<!!!<<< OFFLINE >>>!!!>>> A recent computer security audit has revealed security flaws in the legacy HapMap site that require NCBI to take it down immediately. We regret the inconvenience, but we are required to do this. That said, NCBI was planning to decommission this site in the near future anyway (although not quite so suddenly), as the 1,000 genomes (1KG) project has established itself as a research standard for population genetics and genomics. NCBI has observed a decline in usage of the HapMap dataset and website with its available resources over the past five years and it has come to the end of its useful life. The International HapMap Project is a multi-country effort to identify and catalog genetic similarities and differences in human beings. Using the information in the HapMap, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. The Project is a collaboration among scientists and funding agencies from Japan, the United Kingdom, Canada, China, Nigeria, and the United States. All of the information generated by the Project will be released into the public domain. The goal of the International HapMap Project is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. By making this information freely available, the Project will help biomedical researchers find genes involved in disease and responses to therapeutic drugs. In the initial phase of the Project, genetic data are being gathered from four populations with African, Asian, and European ancestry. Ongoing interactions with members of these populations are addressing potential ethical issues and providing valuable experience in conducting research with identified populations. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. The Project officially started with a meeting in October 2002 (https://www.genome.gov/10005336/) and is expected to take about three years.

Reality Commons

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Cell phones have become an important platform for the understanding of social dynamics and influence, because of their pervasiveness, sensing capabilities, and computational power. Many applications have emerged in recent years in mobile health, mobile banking, location based services, media democracy, and social movements. With these new capabilities, we can potentially be able to identify exact points and times of infection for diseases, determine who most influences us to gain weight or become healthier, know exactly how information flows among employees and productivity emerges in our work spaces, and understand how rumors spread. In an attempt to address these challenges, we release several mobile data sets here in "Reality Commons" that contain the dynamics of several communities of about 100 people each. We invite researchers to propose and submit their own applications of the data to demonstrate the scientific and business values of these data sets, suggest how to meaningfully extend these experiments to larger populations, and develop the math that fits agent-based models or systems dynamics models to larger populations. These data sets were collected with tools developed in the MIT Human Dynamics Lab and are now available as open source projects or at cost.

TheDataWeb

DataFerrett

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<<<!!!<<< This repository is no longer available. >>>!!!>>> Be advised that DataFerrett was decommissioned June 30, 2020; see https://www.census.gov/data/data-tools/dataferrett.html

Antarctic Marine Geology Research Facility

AMGRF

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The Antarctic Research Facility is a national repository for geological materials collected in polar regions. The Facility houses the largest such Southern Ocean collection in the world. These materials have been acquired from over 90 USAP research vessel cruises.

Bigelow National Center for Algae and Microbiota

formerly: CCMP

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The NCMA maintains the largest and most diverse collection of publically available marine algal strains in the world. The algal strains in the collection have been obtained from all over the world, from polar to tropical waters, marine, freshwater, brackish, and hyper-saline environments. New strains (50 - 100 per year) are added largely through the accession of strains deposited by scientists in the community. A stringent accession policy is required to help populate the collection with a diverse range of strains.

The Adaptive Evolution Database

TAED

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TAED is a database of phylogenetically indexed gene families. It contains multiple sequence alignments from MAFFT1, maximum likelihood phylogenetic trees from PhyML2, bootstrap values for each node, dN/dS ratios for each lineage from the free ratios model in PAML3, and labels for each node of speciation or duplication from gene tree/species tree reconciliation using SoftParsMap4. The phylogenetic indexing enables simultaneous viewing of lineages with high dN/dS that occurred along the same species tree branches. Resources from the Protein Data Bank (PDB) and the Kyoto Encyclopedia of Genes and Genomes (KEGG)5, have been incorporated into the TAED analysis to detect substitutions along each branch within the phylogenetic tree and to assess selection within pathways.

GUDMAP

GenitoUrinary Development Molecular Anatomy Project

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The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is a consortium of laboratories working to provide the scientific and medical community with tools to facilitate research. The key components are: (1) a molecular atlas of gene expression for the developing organs of the GenitoUrinary (GU) tract; (2) a high resolution molecular anatomy that highlights development of the GU system; (3) mouse strains to facilitate developmental and functional studies within the GU system; (4) tutorials describing GU organogenesis; and (5) rapid access to primary data via the GUDMAP database.