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Found 622 result(s)
As with most biomedical databases, the first step is to identify relevant data from the research community. The Monarch Initiative is focused primarily on phenotype-related resources. We bring in data associated with those phenotypes so that our users can begin to make connections among other biological entities of interest. We import data from a variety of data sources. With many resources integrated into a single database, we can join across the various data sources to produce integrated views. We have started with the big players including ClinVar and OMIM, but are equally interested in boutique databases. You can learn more about the sources of data that populate our system from our data sources page https://monarchinitiative.org/about/sources.
<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.
The Mikulski Archive for Space Telescopes (MAST) is a NASA funded project to support and provide to the astronomical community a variety of astronomical data archives, with the primary focus on scientifically related data sets in the optical, ultraviolet, and near-infrared parts of the spectrum. MAST is located at the Space Telescope Science Institute (STScI).
The BGS is a data-rich organisation with over 400 datasets in its care; including environmental monitoring data, digital databases, physical collections (borehole core, rocks, minerals and fossils), records and archives. Our data is managed by the National Geoscience Data Centre.
The PDS archives and distributes scientific data from NASA planetary missions, astronomical observations, and laboratory measurements. The PDS is sponsored by NASA's Science Mission Directorate. Its purpose is to ensure the long-term usability of NASA data and to stimulate advanced research
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The Canadian Astronomy Data Centre (CADC) was established in 1986 by the National Research Council of Canada (NRC), through a grant provided by the Canadian Space Agency (CSA). Over the past 30 years the CADC has evolved from an archiving centre---hosting data from Hubble Space Telescope, Canada-France-Hawaii Telescope, the Gemini observatories, and the James Clerk Maxwell Telescope---into a Science Platform for data-intensive astronomy. The CADC, in partnership with Shared Services Canada, Compute Canada, CANARIE and the university community (funded through the Canadian Foundation for Innovation), offers cloud computing, user-managed storage, group management, and data publication services, in addition to its ongoing mission to provide permanent storage for major data collections. Located at NRC Herzberg Astronomy and Astrophysics Research Centre in Victoria, BC, the CADC staff consists of professional astronomers, software developers, and operations staff who work with the community to develop and deliver leading-edge services to advance Canadian research. The CADC plays a leading role in international efforts to improve the scientific/technical landscape that supports data intensive science. This includes leadership roles in the International Virtual Observatory Alliance and participation in organizations like the Research Data Alliance, CODATA, and the World Data Systems. CADC also contributes significantly to future Canadian projects like the Square Kilometre Array and TMT. In 2019, the Canadian Astronomy Data Centre (CADC) delivered over 2 Petabytes of data (over 200 million individual files) to thousands of astronomers in Canada and in over 80 other countries. The cloud processing system completed over 6 million jobs (over 1100 core years) in 2019.
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<<<!!!<<< The repository is no longer available 2020-02-21: no more access to "Environment Climate Data Sweden" >>>!!!<<< The transfer of records from the Environment Climate Data Sweden (ECDS) database to the Swedish National Dataservice (SND) https://www.re3data.org/repository/r3d100010146 was completed in 2019. SND is a national research infrastructure with a primary function to support the accessibility, preservation, and re-use of research data and related materials. You can search the SND research data portal specifically for Natural Science or Agricultural and Veterinary Sciences datasets. Data descriptions with associated datasets, or a direct reference/URL to data, have been migrated from the ECDS portal to the SND research data portal. Previous links to these data are now automatically directed to an SND catalogue entry. Records in the ECDS catalogue that only contained metadata (ie information that data could be accessed through another portal, e.g. Pangea), now link directly to the portal in question. If you want to make one of those data descriptions searchable in SND’s catalogue, please contact SND on snd@snd.gu.se. A small number of records were neither migrated to SND nor redirected to external providers, and they redirect. Contact SND on snd@snd.gu.se if you want more information about the closing of the ECDS portal and the migration of data descriptions to SND’s research data catalogue.
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With Open Science OVGU the Otto-von-Guericke University provides its scientists with a research data repository. Measurement data, laboratory values, survey data, methodical test procedures, etc. can be archived in Open Science OVGU and made available to the scientific community via Open Access.
The University has followed all of the children born in Aberdeen in 1921, 1936, and 1950-1956 as they grow and age. Collectively these groups are known as the ABERDEEN BIRTH COHORTS, and are a jewel in the crown of Scottish health research and have helped to advance our understanding of aging well. The Children of the 1950s study is a population-based resource for the study of biological and social influences on health across the life-course and between generations.
Our knowledge of the many life-forms on Earth - of animals, plants, fungi, protists and bacteria - is scattered around the world in books, journals, databases, websites, specimen collections, and in the minds of people everywhere. Imagine what it would mean if this information could be gathered together and made available to everyone – anywhere – at a moment’s notice. This dream is becoming a reality through the Encyclopedia of Life.
MGI is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease. The projects contributing to this resource are: Mouse Genome Database (MGD) Project, Gene Expression Database (GXD) Project, Mouse Tumor Biology (MTB) Database Project, Gene Ontology (GO) Project at MGI, MouseMine Project, MouseCyc Project at MGI
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The arctic data archive system (ADS) collects observation data and modeling products obtained by various Japanese research projects and gives researchers to access the results. By centrally managing a wide variety of Arctic observation data, we promote the use of data across multiple disciplines. Researchers use these integrated databases to clarify the mechanisms of environmental change in the atmosphere, ocean, land-surface and cryosphere. That ADS will be provide an opportunity of collaboration between modelers and field scientists, can be expected.
The ILO Department of Statistics is the focal point to the United Nations on labour statistics. They develop international standards for better measurement of labour issues and enhanced international comparability; provide relevant, timely and comparable labour statistics; and help Member States develop and improve their labour statistics.
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
CERN, DESY, Fermilab and SLAC have built the next-generation High Energy Physics (HEP) information system, INSPIRE. It combines the successful SPIRES database content, curated at DESY, Fermilab and SLAC, with the Invenio digital library technology developed at CERN. INSPIRE is run by a collaboration of CERN, DESY, Fermilab, IHEP, IN2P3 and SLAC, and interacts closely with HEP publishers, arXiv.org, NASA-ADS, PDG, HEPDATA and other information resources. INSPIRE represents a natural evolution of scholarly communication, built on successful community-based information systems, and provides a vision for information management in other fields of science.
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The Research Data Centre (Forschungsdatenzentrum, FDZ) at the Institute for Educational Quality Improvement (Institut zur Qualitätsentwicklung im Bildungswesen, IQB) archives and documents data sets resulting from national and international assessment studies (such as DESI, PIRLS, PISA, IQB-Bildungstrends). Moreover, the FDZ makes these data sets available for re- and secondary analysis. Members of the scientific community can apply for access to the data sets archived at the FDZ.
The N3C Data Enclave is a secure portal containing a very large and extensive set of harmonized COVID-19 clinical electronic health record (EHR) data. The data can be accessed through a secure cloud Enclave hosted by NCATS and cannot be downloaded due to regulatory control. Broad access is available to investigators at institutions that sign a Data Use Agreements and via Data Use Requests by investigators. The N3C is a unique open, reproducible, transparent, collaborative team science initiative to leverage sensitive clinical data to expedite COVID-19 discoveries and improve health outcomes.
GAWSIS is being developed and maintained by the Federal Office of Meteorology and Climatology MeteoSwiss in collaboration with the WMO GAW Secretariat, the GAW World Data Centres and other GAW representatives to improve the management of information about the GAW network of ground-based stations. The application is presently hosted by the Swiss Laboratories for Materials Testing and Research Empa. GAWSIS provides the GAW community and other interested people with an up-to-date, searchable data base of site descriptions, measurements programs and data available, contact people, bibliographic references. Linked data collections are hosted at the World Data Centers of the WMO Global Atmosphere Watch.
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<<<!!!<<< This repository is no longer available. >>>!!!>>> C3-Grid is an ALREADY FINISHED project within D-Grid, the initiative to promote a grid-based e-Science framework in Germany. The goal of C3-Grid is to support the workflow of Earth system researchers. A grid infrastructure will be implemented that allows efficient distributed data processing and inter-institutional data exchange. Aim of the effort was to develop an infrastructure for uniform access to heterogeneous data and distributed data processing. The work was structured in two projects funded by the Federal Ministry of Education and Research. The first project was part of the D-Grid initiative and explored the potential of grid technology for climate research and developed a prototype infrastructure. Details about the C3Grid architecture are described in “Earth System Modelling – Volume 6”. In the second phase "C3Grid - INAD: Towards an Infrastructure for General Access to Climate Data" this infrastructure was improved especially with respect to interoperability to Earth System Grid Federation (ESGF). Further the portfolio of available diagnostic workflows was expanded. These workflows can be re-used now in adjacent infrastructures MiKlip Evaluation Tool (http://www.fona-miklip.de/en/index.php) and as Web Processes within the Birdhouse Framework (http://bird-house.github.io/). The Birdhouse Framework is now funded as part of the European Copernicus Climate Change Service (https://climate.copernicus.eu/) managed by ECMWF and will be extended to provide scalable processing services for ESGF hosted data at DKRZ as well as IPSL and BADC.
META-SHARE, the open language resource exchange facility, is devoted to the sustainable sharing and dissemination of language resources (LRs) and aims at increasing access to such resources in a global scale. META-SHARE is an open, integrated, secure and interoperable sharing and exchange facility for LRs (datasets and tools) for the Human Language Technologies domain and other applicative domains where language plays a critical role. META-SHARE is implemented in the framework of the META-NET Network of Excellence. It is designed as a network of distributed repositories of LRs, including language data and basic language processing tools (e.g., morphological analysers, PoS taggers, speech recognisers, etc.). Data and tools can be both open and with restricted access rights, free and for-a-fee.
WFCC Global Catalogue of Microorganisms (GCM) is expected to be a robust, reliable and user-friendly system to help culture collections to manage, disseminate and share the information related to their holdings. It also provides a uniform interface for the scientific and industrial communities to access the comprehensive microbial resource information.
The Breast Cancer Surveillance Consortium (BCSC) is a research resource for studies designed to assess the delivery and quality of breast cancer screening and related patient outcomes in the United States. The BCSC is a collaborative network of seven mammography registries with linkages to tumor and/or pathology registries. The network is supported by a central Statistical Coordinating Center.
The BioStudies database holds descriptions of biological studies, links to data from these studies in other databases at EMBL-EBI or outside, as well as data that do not fit in the structured archives at EMBL-EBI. The database accepts submissions via an online tool, or in a simple tab-delimited format. It also enables authors to submit supplementary information and link to it from the publication.