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Found 165 result(s)
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<<<!!!<<< This repository is no longer available. >>>!!!>>> The main objective of our work is to understand the pathomechanisms of late onset neurodegenerative disorders such as Huntington's, Parkinson's, Alzheimer's and Machado Joseph disease and to develop causal therapies for them. The disease causing proteins of these illnesses have been identified, but their functions in the unaffected organism are mostly unknown. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD).
The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database currently hosts DNA binding data for 406 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse, and human. The database's web tools (on the right) include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences
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Nobeyama Radio Polarimeters (NoRP) are observing the Sun with multiple frequencies in the microwave range. It is capable to obtain the total coming flux and the circular-polarization degree.
The POES satellite system offers the advantage of daily global coverage, by making nearly polar orbits 14 times per day approximately 520 miles above the surface of the Earth. The Earth's rotation allows the satellite to see a different view with each orbit, and each satellite provides two complete views of weather around the world each day. NOAA partners with the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT) to constantly operate two polar-orbiting satellites – one POES and one European polar-orbiting satellite called Metop. NOAA's Polar Orbiting Environmental Satellites (POES) carry a suite of instruments that measure the flux of energetic ions and electrons at the altitude of the satellite. This environment varies as a result of solar and geomagnetic activity. Beginning with the NOAA-15 satellite, an upgraded version of the Space Environment Monitor (SEM-2) has been flown.
>>>!!!<<< 2019-12-03: The repository is no longer available >>>!!!<<< Please use https://www.cfa.harvard.edu/amp/ampdata/kurucz23/sekur.html The atomic line data used in this database are taken from Bob Kurucz' CD-ROM 23 of spectroscopic line calculations. The database contains all lines of the file "gfall.dat" with the following items for each line: Wavelength; loggf; element code; lower level: energy, J, configuration; upper level: energy, J, configuration; gamma r; gamma s; gamma w; reference code. CD-ROM 23 has all the atomic line data with good wavelengths in one large file and in one file for each species. The big file is also divided into 10 nm and 100 nm sections for convenience. Also given are hyperfine line lists for neutral Sc, V, Mn, and Co that were produced by splitting all the energy levels for which laboratory data are available (only a small fraction).
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The AMIGA project (Analysis of the interstellar Medium of Isolated GAlaxies) involves the identification and study of a statistically significant sample of the most isolated galaxies in the local Universe. Our goal is to quantify the properties of different phases of the interstellar medium in these galaxies which are likely to be least affected by their external environment.
OpenWorm aims to build the first comprehensive computational model of the Caenorhabditis elegans (C. elegans), a microscopic roundworm. With only a thousand cells, it solves basic problems such as feeding, mate-finding and predator avoidance. Despite being extremely well studied in biology, this organism still eludes a deep, principled understanding of its biology. We are using a bottom-up approach, aimed at observing the worm behaviour emerge from a simulation of data derived from scientific experiments carried out over the past decade. To do so we are incorporating the data available in the scientific community into software models. We are engineering Geppetto and Sibernetic, open-source simulation platforms, to be able to run these different models in concert. We are also forging new collaborations with universities and research institutes to collect data that fill in the gaps All the code we produce in the OpenWorm project is Open Source and available on GitHub.
Genome track alignments using GBrowse on this site are featured with: (1) Annotated and predicted genes and transcripts; (2) QTL / SNP Association tracks; (3) OMIA genes; (4) Various SNP Chip tracks; (5) Other mapping fetures or elements that are available.
KDP has replaced the KNMI Data Centre (KDC), which was turned off on the 27th of July 2020. Not only a change of name, but also a transition to new technologies. Initially, the KDP will be more primitive than KDC. To fulfill future ambitions, a digital KNMI transformation has been initiated. Part of this transition is the development of a new KDP as a successor of the KDC. All data on the KNMI Data Platform is free to use. For some datasets a service agreement is available, which is indicated on the page of the dataset. The KNMI Data platform provides access to KNMI data on weather, climate and seismology. Here you will find KNMI data on various subjects such as the most recent 10-minute observations, historical series, data about meteorological measuring stations, model calculations, earthquake data and satellite products. In addition to KNMI datasets, we also make datasets from other parties available, such as ECMWF, ECOMET, EUMETSAT and WMO.
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GABI, acronym for "Genomanalyse im biologischen System Pflanze", is the name of a large collaborative network of different plant genomic research projects. Plant data from different ‘omics’ fronts representing more than 10 different model or crop species are integrated in GabiPD.
NASA funded OpenAltimetry facilitates the advanced discovery, processing, and visualization services for ICESat and ICESat-2 altimeter data.
<<<!!!<<< This repository is no longer available. >>>!!!>>> The sequencing of several bird genomes and the anticipated sequencing of many more provided the impetus to develop a model organism database devoted to the taxonomic class: Aves. Birds provide model organisms important to the study of neurobiology, immunology, genetics, development, oncology, virology, cardiovascular biology, evolution and a variety of other life sciences. Many bird species are also important to agriculture, providing an enormous worldwide food source worldwide. Genomic approaches are proving invaluable to studying traits that affect meat yield, disease resistance, behavior, and bone development along with many other factors affecting productivity. In this context, BirdBase will serve both biomedical and agricultural researchers.
The Barrow, Alaska Observatory (BRW) archives and provides digital access to their findings related to climate change, ozone depletion and baseline air quality. The BRW is part of the National Oceanic and Atmospheric Administration and Earth System Research Laboratory Global Monitoring Division.
The MPC is responsible for the designation of minor bodies in the solar system: minor planets; comets, in conjunction with the Central Bureau for Astronomical Telegrams (CBAT); and natural satellites (also in conjunction with CBAT). The MPC is also responsible for the efficient collection, computation, checking and dissemination of astrometric observations and orbits for minor planets and comets
The U.S. launched the Joint Global Ocean Flux Study (JGOFS) in the late 1980s to study the ocean carbon cycle. An ambitious goal was set to understand the controls on the concentrations and fluxes of carbon and associated nutrients in the ocean. A new field of ocean biogeochemistry emerged with an emphasis on quality measurements of carbon system parameters and interdisciplinary field studies of the biological, chemical and physical process which control the ocean carbon cycle. As we studied ocean biogeochemistry, we learned that our simple views of carbon uptake and transport were severely limited, and a new "wave" of ocean science was born. U.S. JGOFS has been supported primarily by the U.S. National Science Foundation in collaboration with the National Oceanic and Atmospheric Administration, the National Aeronautics and Space Administration, the Department of Energy and the Office of Naval Research. U.S. JGOFS, ended in 2005 with the conclusion of the Synthesis and Modeling Project (SMP).
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This guide aims to provide a starting point to locating Geographic Information System (GIS) information both through the University of Sydney library catalogue and on the World Wide Web.
EartH2Observe brings together the findings from European FP projects DEWFORA, GLOWASIS, WATCH, GEOWOW and others. It will integrate available global earth observations (EO), in-situ datasets and models and will construct a global water resources re-analysis dataset of significant length (several decades). The resulting data will allow for improved insights on the full extent of available water and existing pressures on global water resources in all parts of the water cycle. The project will support efficient and globally consistent water management and decision making by providing comprehensive multi-scale (regional, continental and global) water resources observations. It will test new EO data sources, extend existing processing algorithms and combine data from multiple satellite missions in order to improve the overall resolution and reliability of EO data included in the re-analysis dataset. The resulting datasets will be made available through an open Water Cycle Integrator data portal https://wci.earth2observe.eu/ : the European contribution to the GEOSS/WCI approach. The datasets will be downscaled for application in case-studies at regional and local levels, and optimized based on identified European and local needs supporting water management and decision making . Actual data access: https://wci.earth2observe.eu/data/group/earth2observe
MicrosporidiaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the phylum Microsporidia. In its first iteration (released in early 2010), MicrosporidiaDB contains the genomes of two Encephalitozoon species (see below). MicrosporidiaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
CryptoDB is an integrated genomic and functional genomic database for the parasite Cryptosporidium and other related genera. CryptoDB integrates whole genome sequence and annotation along with experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
The European Union Open Data Portal is the single point of access to a growing range of data from the institutions and other bodies of the European Union (EU). Data are free for you to use and reuse for commercial or non-commercial purposes. By providing easy and free access to data, the portal aims to promote their innovative use and unleash their economic potential. It also aims to help foster the transparency and the accountability of the institutions and other bodies of the EU. The EU Open Data Portal is managed by the Publications Office of the European Union. Implementation of the EU's open data policy is the responsibility of the Directorate-General for Communications Networks, Content and Technology of the European Commission.
MassBank of North America (MoNA) is a metadata-centric, auto-curating repository designed for efficient storage and querying of mass spectral records. It intends to serve as a the framework for a centralized, collaborative database of metabolite mass spectra, metadata and associated compounds. MoNA currently contains over 200,000 mass spectral records from experimental and in-silico libraries as well as from user contributions.