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Found 20 result(s)
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
FungiDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the kingdom Fungi. FungiDB was first released in early 2011 as a collaborative project between EuPathDB and the group of Jason Stajich (University of California, Riverside). At the end of 2015, FungiDB was integrated into the EuPathDB bioinformatic resource center. FungiDB integrates whole genome sequence and annotation and also includes experimental and environmental isolate sequence data. The database includes comparative genomics, analysis of gene expression, and supplemental bioinformatics analyses and a web interface for data-mining.
The Duke Research Data Repository is a service of the Duke University Libraries that provides curation, access, and preservation of research data produced by the Duke community. Duke's RDR is a discipline agnostic institutional data repository that is intended to preserve and make public data related to the teaching and research mission of Duke University including data linked to a publication, research project, and/or class, as well as supplementary software code and documentation used to provide context for the data.
A research data repository for the education and developmental sciences.
TriTrypDB is an integrated genomic and functional genomic database for pathogens of the family Trypanosomatidae, including organisms in both Leishmania and Trypanosoma genera. TriTrypDB and its continued development are possible through the collaborative efforts between EuPathDB, GeneDB and colleagues at the Seattle Biomedical Research Institute (SBRI).
Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.
The Energy Data Centre holds information relating to energy research, focused on the UK. It has a research data catalogue, information on publications resulting from the UK Energy Research Centre and the Energy Technologies Institute and energy research related grants.
VectorBase provides data on arthropod vectors of human pathogens. Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. VectorBase also offers genome browser, gene expression and microarray repository, and BLAST searches for all VectorBase genomes. VectorBase Genomes include Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Ixodes scapularis, Pediculus humanus, Rhodnius prolixus. VectorBase is one the Bioinformatics Resource Centers (BRC) projects which is funded by National Institute of Allergy and Infectious Diseases (NAID).
The Maize Genetics and Genomics Database focuses on collecting data related to the crop plant and model organism Zea mays. The project's goals are to synthesize, display, and provide access to maize genomics and genetics data, prioritizing mutant and phenotype data and tools, structural and genetic map sets, and gene models. MaizeGDB also aims to make the Maize Newsletter available, and provide support services to the community of maize researchers. MaizeGDB is working with the Schnable lab, the Panzea project, The Genome Reference Consortium, and iPlant Collaborative to create a plan for archiving, dessiminating, visualizing, and analyzing diversity data. MMaizeGDB is short for Maize Genetics/Genomics Database. It is a USDA/ARS funded project to integrate the data found in MaizeDB and ZmDB into a single schema, develop an effective interface to access this data, and develop additional tools to make data analysis easier. Our goal in the long term is a true next-generation online maize database.aize genetics and genomics database.
The mission of World Data Center for Climate (WDCC) is to provide central support for the German and European climate research community. The WDCC is member of the ISC's World Data System. Emphasis is on development and implementation of best practice methods for Earth System data management. Data for and from climate research are collected, stored and disseminated. The WDCC is restricted to data products. Cooperations exist with thematically corresponding data centres of, e.g., earth observation, meteorology, oceanography, paleo climate and environmental sciences. The services of WDCC are also available to external users at cost price. A special service for the direct integration of research data in scientific publications has been developed. The editorial process at WDCC ensures the quality of metadata and research data in collaboration with the data producers. A citation code and a digital identifier (DOI) are provided and registered together with citation information at the DOI registration agency DataCite.
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Jülich DATA is a registry service to index all research data created at or in the context of Forschungszentrum Jülich. As an institutionial repository, it may also be used for data and software publications.
MicrosporidiaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the phylum Microsporidia. In its first iteration (released in early 2010), MicrosporidiaDB contains the genomes of two Encephalitozoon species (see below). MicrosporidiaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
The Immunology Database and Analysis Portal (ImmPort) archives clinical study and trial data generated by NIAID/DAIT-funded investigators. Data types housed in ImmPort include subject assessments i.e., medical history, concomitant medications and adverse events as well as mechanistic assay data such as flow cytometry, ELISA, ELISPOT, etc. --- You won't need an ImmPort account to search for compelling studies, peruse study demographics, interventions and mechanistic assays. But why stop there? What you really want to do is download the study, look at each experiment in detail including individual ELISA results and flow cytometry files. Perhaps you want to take those flow cytometry files for a test drive using FLOCK in the ImmPort flow cytometry module. To download all that interesting data you will need to register for ImmPort access.
EuPathDB (formerly ApiDB) is an integrated database covering the eukaryotic pathogens in the genera Acanthamoeba, Annacaliia, Babesia, Crithidia, Cryptosporidium, Edhazardia, Eimeria, Encephalitozoon, Endotrypanum, Entamoeba, Enterocytozoon, Giardia, Gregarina, Hamiltosporidium, Leishmania, Nematocida, Neospora, Nosema, Plasmodium, Theileria, Toxoplasma, Trichomonas, Trypanosoma and Vavraia, Vittaforma). While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all of these resources, and the opportunity to leverage orthology for searches across genera.
The ADS is an accredited digital repository for heritage data that supports research, learning and teaching with freely available, high quality and dependable digital resources by preserving and disseminating digital data in the long term. The ADS also promotes good practice in the use of digital data, provides technical advice to the heritage community, and supports the deployment of digital technologies.
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The Research Data Center Qualiservice provides services for archiving and reusing qualitative research data from the social sciences. We advise and accompany research projects in the process of long-term data archiving and data sharing. Data curation is conducted by experts for the social sciences. We also provide research data and relevant context information for reuse in scientific research and teaching. Internationally interoperable metadata ensure that data sets are searchable and findable. Persistent identifiers (DOI) ensure that data and study contexts are citable. Qualiservice was accredited by the German Data Forum (RatSWD) in 2019 and adheres to its quality assurance criteria. Qualiservice is committed to the German Research Foundation’s (DFG) Guidelines for Safeguarding Good Scientific Practice and takes into account the FAIR Guiding Principles for scientific data management and stewardship as well as the OECD Principles and Guidelines for Access to Research Data from Public Funding. Qualiservice coordinates the networking and further development of scientific infrastructures for archiving and secondary use of qualitative data from social research within the framework of the National Research Data Infrastructure.
Apollo (previously DSpace@Cambridge) is the University of Cambridge’s Institutional Repository (IR), preserving and providing access to content created by members of the University. The repository stores a range of content and provides different levels of access, but its primary focus is on providing open access to the University’s research publications.
Yabelana is a data repository of the University of KwaZulu-Natal (UKZN) which was developed to preserve, manage and share UKZN-Researchers research data; which include figures, datasets, software/code, images, videos, posters presentations.