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During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome (spindle pole in budding yeast), kinetochore/centromere, cleavage furrow/midbody (related or homolog structures in plants and budding yeast called as phragmoplast and bud neck, respectively), telomere and spindle spatially and temporally. These sub-cellular regions play important roles in various biological processes. In this work, we have collected all proteins identified to be localized on kinetochore, centrosome, midbody, telomere and spindle from two fungi (S. cerevisiae and S. pombe) and five animals, including C. elegans, D. melanogaster, X. laevis, M. musculus and H. sapiens based on the rationale of "Seeing is believing" (Bloom K et al., 2005). Through ortholog searches, the proteins potentially localized at these sub-cellular regions were detected in 144 eukaryotes. Then the integrated and searchable database MiCroKiTS - Midbody, Centrosome, Kinetochore, Telomere and Spindle has been established.
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Strasbourg astronomical Data Center (CDS) is dedicated to the collection and worldwide distribution of astronomical data and related information. Alongside data curation and service maintenance responsibilities, the CDS undertakes R&D activities that are fundamental to ensure the long term sustainability in a domain in which technology evolves very quickly. R&D areas include informatics, big data, and development of the astronomical Virtual Observatory (VO). CDS is a major actor in the VO with leading roles in European VO projects, the French Virtual Observatory and the International Virtual Observatory Alliance (IVOA). The CDS hosts the SIMBAD astronomical database, the world reference database for the identification of astronomical objects; VizieR, the catalogue service for the CDS reference collection of astronomical catalogues and tables published in academic journals; and the Aladin interactive software sky atlas for access, visualization and analysis of astronomical images, surveys, catalogues, databases and related data.
<<<!!!<<< This repository is no longer available. >>>!!!>>> BioVeL is a virtual e-laboratory that supports research on biodiversity issues using large amounts of data from cross-disciplinary sources. BioVeL supports the development and use of workflows to process data. It offers the possibility to either use already made workflows or create own. BioVeL workflows are stored in MyExperiment - Biovel Group http://www.myexperiment.org/groups/643/content. They are underpinned by a range of analytical and data processing functions (generally provided as Web Services or R scripts) to support common biodiversity analysis tasks. You can find the Web Services catalogued in the BiodiversityCatalogue.
RunMyCode is a novel cloud-based platform that enables scientists to openly share the code and data that underlie their research publications. The web service only requires a web browser as all calculations are done on a dedicated cloud computer. Once the results are ready, they are automatically displayed to the user.
The THREDDS Data Server (TDS) is a web server that provides metadata and data access for scientific datasets, using OPeNDAP, OGC WMS and WCS, HTTP, and other remote data access protocols. Unidata is a diverse community of over 250 institutions vested in the common goal of sharing data, and tools to access and visualize that data. For more than 25 years Unidata has been providing data, tools, and support to enhance earth-system education and research. In an era of increasing data complexity, accessibility, and multidisciplinary integration, Unidata provides a rich set of services and tools.
IVS is an international collaboration of organizations which operate or support Very Long Baseline Interferometry (VLB I) components. The service aspect of IVS is meant to serve both outside users and the geodetic and astrometric community itself. Both the contributors and users of data will be served.
ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data). The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.
California Digital Library (CDL) seeks to be a catalyst for deeply collaborative solutions providing a rich, intuitive and seamless environment for publishing, sharing and preserving our scholars’ increasingly diverse outputs, as well as for acquiring and accessing information critical to the University of California’s scholarly enterprise. University of California Curation Center (UC3) is the digital curation program within CDL. The mission of UC3 is to provide transformative preservation, curation, and research data management systems, services, and initiatives that sustain and promote open scholarship.