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ALSoD is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene to a multigene ALS bioinformatics repository and analytical instrument combining genotype, phenotype, and geographical information with associated analysis tools. These include a comparison tool to evaluate genes side by side or jointly with user configurable features, a pathogenicity prediction tool using a combination of computational approaches to distinguish variants with nonfunctional characteristics from disease-associated mutations with more dangerous consequences, and a credibility tool to enable ALS researchers to objectively assess the evidence for gene causation in ALS. Furthermore, integration of external tools, systems for feedback, annotation by users, and two-way links to collaborators hosting complementary databases further enhance the functionality of ALSoD.
The Intermediate Filament Database will function as a continuously updated review of the intermediate filament field and it is hoped that users will contribute to the development and expansion of the database on a regular basis. Contributions may include novel variants, new patients with previously discovered sequence and allelic variants. Suggestions on ways to improve the database are also welcome.
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KRISHI Portal is an initiative of Indian Council of Agricultural Research (ICAR) to bring its knowledge resources to all stakeholders at one place. The portal is being developed as a centralized data repository system of ICAR consisting of Technology, Data generated through Experiments/ Surveys/ Observational studies, Geo-spatial data, Publications, Learning Resources etc. For implementation of research data management electronically in ICAR Institutes and digitization of agricultural research, KRISHI (Knowledge based Resources Information Systems Hub for Innovations in Agriculture) Portal has been developed as ICAR Research Data Repository for knowledge management. Data Inventory Repository aims at creating Meta Data Inventory through information related to data availability at Institute level. The portal consists of six repositories viz. technology, publication, experimental data, observational data survey data and geo-portal. The portal can be accessed at http://krishi.icar.gov.in. During the period of 2016-17, input data on latitude and longitude of all KVKs under this Zone was submitted to the concerned authority to put them in geo-portal. One brainstorming session was organized at this institute for all scientists on its use and uploading information in portal. As per guidelines of the council, various kinds of publications pertaining to this institute were also uploaded in this portal.