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The PRISM Climate Group gathers climate observations from a wide range of monitoring networks, applies sophisticated quality control measures, and develops spatial climate datasets to reveal short- and long-term climate patterns. The resulting datasets incorporate a variety of modeling techniques and are available at multiple spatial/temporal resolutions, covering the period from 1895 to the present. Whenever possible, we offer these datasets to the public, either free of charge or for a fee (depending on dataset size/complexity and funding available for the activity).
BindingDB is a public, web-accessible knowledgebase of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. BindingDB supports medicinal chemistry and drug discovery via literature awareness and development of structure-activity relations (SAR and QSAR); validation of computational chemistry and molecular modeling approaches such as docking, scoring and free energy methods; chemical biology and chemical genomics; and basic studies of the physical chemistry of molecular recognition. BindingDB also includes a small collection of host-guest binding data of interest to chemists studying supramolecular systems. The data collection derives from a variety of measurement techniques, including enzyme inhibition and kinetics, isothermal titration calorimetry, NMR, and radioligand and competition assays. BindingDB includes data extracted from the literature and from US Patents by the BindingDB project, selected PubChem confirmatory BioAssays, and ChEMBL entries for which a well defined protein target ("TARGET_TYPE='PROTEIN'") is provided.
The DesignSafe Data Depot Repository (DDR) is the platform for curation and publication of datasets generated in the course of natural hazards research. The DDR is an open access data repository that enables data producers to safely store, share, organize, and describe research data, towards permanent publication, distribution, and impact evaluation. The DDR allows data consumers to discover, search for, access, and reuse published data in an effort to accelerate research discovery. It is a component of the DesignSafe cyberinfrastructure, which represents a comprehensive research environment that provides cloud-based tools to manage, analyze, curate, and publish critical data for research to understand the impacts of natural hazards. DesignSafe is part of the NSF-supported Natural Hazards Engineering Research Infrastructure (NHERI), and aligns with its mission to provide the natural hazards research community with open access, shared-use scholarship, education, and community resources aimed at supporting civil and social infrastructure prior to, during, and following natural disasters. It serves a broad national and international audience of natural hazard researchers (both engineers and social scientists), students, practitioners, policy makers, as well as the general public. It has been in operation since 2016, and also provides access to legacy data dating from about 2005. These legacy data were generated as part of the NSF-supported Network for Earthquake Engineering Simulation (NEES), a predecessor to NHERI. Legacy data and metadata belonging to NEES were transferred to the DDR for continuous preservation and access.