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As with most biomedical databases, the first step is to identify relevant data from the research community. The Monarch Initiative is focused primarily on phenotype-related resources. We bring in data associated with those phenotypes so that our users can begin to make connections among other biological entities of interest. We import data from a variety of data sources. With many resources integrated into a single database, we can join across the various data sources to produce integrated views. We have started with the big players including ClinVar and OMIM, but are equally interested in boutique databases. You can learn more about the sources of data that populate our system from our data sources page https://monarchinitiative.org/about/sources.
iNaturalist is a citizen science project and online social network of naturalists, citizen scientists, and biologists built on the concept of mapping and sharing observations of biodiversity across the globe. iNat is a platform for biodiversity research, where anyone can start up their own science project with a specific purpose and collaborate with other observers.
DATA.NASA.GOV is NASA's clearinghouse site for open-data provided to the public. Tens of thousands of datasets are available for you. This site is a continually growing catalog of publicly available NASA Datasets, APIs, Visualizations, and more.
TAED is a database of phylogenetically indexed gene families. It contains multiple sequence alignments from MAFFT1, maximum likelihood phylogenetic trees from PhyML2, bootstrap values for each node, dN/dS ratios for each lineage from the free ratios model in PAML3, and labels for each node of speciation or duplication from gene tree/species tree reconciliation using SoftParsMap4. The phylogenetic indexing enables simultaneous viewing of lineages with high dN/dS that occurred along the same species tree branches. Resources from the Protein Data Bank (PDB) and the Kyoto Encyclopedia of Genes and Genomes (KEGG)5, have been incorporated into the TAED analysis to detect substitutions along each branch within the phylogenetic tree and to assess selection within pathways.
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This study assessed differences in avian biodiversity across different forest age-classes, including mature stands (> 100 years), in a managed, mixed-species eucalypt forest located in Gippsland, south-eastern Australia. Avian surveys and detailed habitat measurements were initially carried out in 50 two hectare stands ranging in age from 100 years. Extensive wildfire which occurred during the study reduced the number of sites to 28 (seven in each of four age classes) upon which analyses and inferences were made. Mature vegetation (> 100 years) had the greatest richness, abundance and biomass of birds. Key ecological resources, such as tree-hollows for nesting, generally occurred mostly in stands > 60 years. There were quantum increases in all measures of avian biodiversity in mature stands (> 100 years). The visualisation of the survey data is part of an interoperable web-GIS maintained by the Centre for eResearch and Digital Innovation (CeRDI) at Federation University Australia (FedUni).